Protein Info for BBR_RS11470 in Bifidobacterium breve UCC2003

Annotation: 6-phosphogluconolactonase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01182: Glucosamine_iso
  • amino acids 15 to 270 (256 residues), 198.5 bits, E=7.2e-63

Best Hits

KEGG orthology group: K01057, 6-phosphogluconolactonase [EC: 3.1.1.31] (inferred from 89% identity to bln:Blon_0208)

Predicted SEED Role

"6-phosphogluconolactonase (EC 3.1.1.31), eukaryotic type" in subsystem Entner-Doudoroff Pathway or Pentose phosphate pathway (EC 3.1.1.31)

MetaCyc Pathways

• heterolactic fermentation (16/18 steps found)
• pentose phosphate pathway (8/8 steps found)
• superpathway of glucose and xylose degradation (14/17 steps found)
• pentose phosphate pathway (oxidative branch) I (3/3 steps found)
• Entner-Doudoroff pathway I (7/9 steps found)
• superpathway of glycolysis and the Entner-Doudoroff pathway (12/17 steps found)
• formaldehyde oxidation I (3/6 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Biosynthesis of plant hormones
• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.31

Protein Sequence (280 amino acids)

>BBR_RS11470 6-phosphogluconolactonase (Bifidobacterium breve UCC2003)
MATRKLVVYPDKDLMIQAGAQRFALALLDLLAERLPDSTHRTRVDVALSGGSAAQPLGLV
LDDPLAEAIDWSRVHFWWSDERFVPAYDTDRNALEARRLLLDKLVADGKLPESNIHEMAA
DVRSTDEIADAMANAESDDDAVRAAADAANDALLDAAARDYEAELIRELGPKPTIDLMIL
GMGPDGHYASLFPGHDEVKVTDRLAVGVNHSPKMPPLRVSLTAPMIASSRRTWFFAAGAS
KVDSLAHVFSKPNNPNYPSSYANGVDEFIWFSTEETVTKL