Protein Info for BBR_RS11225 in Bifidobacterium breve UCC2003

Annotation: dipeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03577: Peptidase_C69
  • amino acids 2 to 427 (426 residues), 647.1 bits, E=5.7e-199

Best Hits

Swiss-Prot: 96% identical to PEPD_BIFLO: Dipeptidase (pepD) from Bifidobacterium longum (strain NCC 2705)

KEGG orthology group: K08659, dipeptidase [EC: 3.4.-.-] (inferred from 96% identity to bln:Blon_0180)

Predicted SEED Role

"putative dipeptidase"

KEGG Metabolic Maps

• Biotin metabolism
• Lysine degradation
• Peptidoglycan biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 3.4.-.-

Use Curated BLAST to search for 3.4.-.-

Protein Sequence (533 amino acids)

>BBR_RS11225 dipeptidase (Bifidobacterium breve UCC2003)
MACTTILVGKDASYDGSTIIARNEDSANGEFNPKRFIVVKPSEQPREYKSVISHLAITLP
DNPLQYTAVPNADLKEGIWGEAGVNEANVAMSATETLTTNERVLGADPFVEYVPAKGNEP
EVPGGIGEEDFLTIVLPYVETAREGVARLGSLLEEFGTYEMNGVAFSDSNEIWWLETVGG
HHWIAKRVPDEAYVTMPNQLGIDEFDLEDALGDQEEYMCSEDLAEFIETNHLDLAVENTT
PFNPRDAFGSHSDSDHVYNTPRAWYMQRFLNPYDEVWDGPDADHKPTSDDIPWARQPERK
VTIEDIKYVLSSHYQGTPFDPYGQLGDERTRHMYRPIGINRQSQLSVMQIRPYRPQASRA
VQWIAYGSNPFNTLVPFFPNVDVTPAYLEDTTTRVTSENFYWVNRIIAALCDGAFRSTSN
AVERYQEKTGAMGHRLVAATDEQIARLGLTAAEEAAQSAAEEEFEADNVDGDVQPMEPDE
IIAALRNPEVREILAAANQTMADQLKEETDKLLDSVLYTRSMEMKNGFHMSDF