Protein Info for BBR_RS11195 in Bifidobacterium breve UCC2003

Annotation: DNA polymerase III subunit delta'

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13177: DNA_pol3_delta2
  • amino acids 10 to 166 (157 residues), 123.8 bits, E=1.1e-39
• PF00004: AAA
  • amino acids 33 to 161 (129 residues), 31.5 bits, E=3.3e-11

Best Hits

KEGG orthology group: K02341, DNA polymerase III subunit delta' [EC: 2.7.7.7] (inferred from 97% identity to bln:Blon_0175)

Predicted SEED Role

"DNA polymerase III delta prime subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

• Purine metabolism
• Pyrimidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Protein Sequence (383 amino acids)

>BBR_RS11195 DNA polymerase III subunit delta' (Bifidobacterium breve UCC2003)
MSVWDSLVGQQPVIDMLSRIAQGDPSQIAQSWLICGPPGSGRSNMARAFAAALESPDHGM
SDEPTRVTQQVLAGTHPDVTVLATNKVTIGIDQVREIITTSEQMPATAPWRIIIIEDVDR
MLERTTNVLLKEIEEPAEHCIWLLCAPSAQDVLPTIRSRTRIVNLAVPSASAVAGFLTAT
TGVEPKVAQRAARLAEGHIGIAKLYATDEQVMTDRDELVVGVLNLARASDAVLLAGNLID
NAKAQAEVDASRTAADQEAEFRRINGLEPGERIPPKLRGAFNQIAKKDDLKRLTTRRTRD
VLDRALNSIASIYRDVAVLQNNAEDSVGLINLENRSAITELSVRLNRAGAVARLDEVAHA
RKRLAGNGNPLLVFESLFCALIP