Protein Info for BBR_RS10910 in Bifidobacterium breve UCC2003

Annotation: molecular chaperone DnaJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 PF00226: DnaJ" amino acids 10 to 71 (62 residues), 92.9 bits, see alignment E=1e-30 PF01556: DnaJ_C" amino acids 174 to 314 (141 residues), 116.8 bits, see alignment E=9e-38

Best Hits

KEGG orthology group: K03686, molecular chaperone DnaJ (inferred from 95% identity to bln:Blon_0143)

Predicted SEED Role

"Chaperone protein DnaJ" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (337 amino acids)

>BBR_RS10910 molecular chaperone DnaJ (Bifidobacterium breve UCC2003)
MAENEWLSKDFYKVLGVSKDASDDDIKKAYRKLARKYHPDVNKTKEAEEKFKDISEAYDV
LSKKEDRQKYDAIRQFGMGGARFAGGSGAGGFDASGFSDIFGSMFGQGAGGNGSRIRFST
SGGGNPNLNDIFSMFGGAAGQGAGGYGQQAYGNAGGYGYEEAPRPENGEDRNSKISLTLR
QAVKGATVSLSVDGKKFKAHVPAGVKDGQKIKLAGKGKPGINGGKAGDLYLHVTVNPDST
FSMRGRDIVMNLPVTVGQAVAGGKVDAKDIDGNLVTFKVPAGSSSGAEVKLAGLGVKRGN
QPGDLIGRVQIMVPAKPGLAVKHAAKEFDEKAGDYLN