Protein Info for BBR_RS10840 in Bifidobacterium breve UCC2003

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF00356: LacI" amino acids 6 to 49 (44 residues), 50.6 bits, see alignment 2.6e-17 PF13407: Peripla_BP_4" amino acids 66 to 312 (247 residues), 39 bits, see alignment E=1.4e-13 PF00532: Peripla_BP_1" amino acids 69 to 293 (225 residues), 28.8 bits, see alignment E=1.8e-10 PF13377: Peripla_BP_3" amino acids 171 to 332 (162 residues), 100.6 bits, see alignment E=2.2e-32

Best Hits

KEGG orthology group: None (inferred from 82% identity to blo:BL0528)

Predicted SEED Role

"MSM (multiple sugar metabolism) operon regulatory protein" in subsystem Fructooligosaccharides(FOS) and Raffinose Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (343 amino acids)

>BBR_RS10840 LacI family transcriptional regulator (Bifidobacterium breve UCC2003)
MAKASIQAVAKEAGVSVSTVSRTFAKPDLVLPETRDKVMAAAEKLDYSISRSAAALKSGQ
SFRIALLASETITTWFNANIFAGLDSVLRPAGYDTVAYPMRNAEERHDFFADLPVRRNAD
AVIVSSFNIEPAEVERLKHMHVPIIGINIPSTDGFDSGVSIDDRTATRAAVEHLIALGHR
GIAFVGGTPAETNMRYSAESRLQGVLDAQAAHPELTVTNLQVPRGATETSAALNAVLTAP
AGTTAFCFEDDELALPVLYRLRQYGKRVPQDISIVGFDDVEMSQAVGLTTMHQDPFAMGA
DAGRMALEAIAGGPIEPAFIQPDAPLVLRETTAPPAAPVPAQG