Protein Info for BBR_RS10635 in Bifidobacterium breve UCC2003

Annotation: Xaa-Pro dipeptidyl-peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 956 PF00930: DPPIV_N" amino acids 255 to 409 (155 residues), 65.1 bits, see alignment E=9.8e-22 PF02129: Peptidase_S15" amino acids 680 to 859 (180 residues), 37 bits, see alignment E=6.5e-13 PF00326: Peptidase_S9" amino acids 719 to 773 (55 residues), 42.5 bits, see alignment 1.1e-14 amino acids 818 to 955 (138 residues), 90.1 bits, see alignment E=2.9e-29

Best Hits

Predicted SEED Role

"peptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (956 amino acids)

>BBR_RS10635 Xaa-Pro dipeptidyl-peptidase (Bifidobacterium breve UCC2003)
MSETNDVTDAIANLPRRRARTLRFTCGAPRSAQTIGNGSRALFLRSDGPEDLVTALWLSW
FDDSSEHHETKLADPRELLGATADSENVPAEEKARRERAREGGAGIVSYSVDADGDRVVF
TINGRLFLTEIGNDAATGAPTSRTRELAGEWLDEDPAMYTPVLNPRIAPDGEHVLYTTGT
YLMLVDIGDWPAEGEPFEVPEGELDNGVEVEADAEESALSEGLYGDEEDGDQPLTDRITA
IYGVSVEDEDGNPADNTWKIGLAEFVAGEEMDRYDGFWWSPDSQHVLFESFDTADEPTWY
ISDPANPETAATGRRYPRALTRNADVYLTVISLAFDENYRYAGITGNADVAWDREAYEYV
AAVNWQLGHDPLVLVQNRRQTRDQVLEVAVETAEEPEALSDDVAATWAQAASADQSERIV
ETDVVEFGGDNEIGETSSFASSAPTLGATRVLEEHANEQWIDLIQGTPAYTTDGRLVCSL
NDMDTDTNRLTVDGRPFTPAGWNVRTVLDVTDTDVLAVVQRAPEIAPEVPSAWAESSDDD
GTTNGAGASDESIASMIGGHDARSFDVVSIDYSGDITPVTTVPGQWTASRAEHGMVVSGR
DMTHANAQMFHILGSPLRGELAAKRTEGSAPVTTETPLNLPTADSSSQGEGPAEATIAST
AAEPGFTPNVTFTRLGEHQMYTAIIAPSPESPYAHADKLPVLMKPYGGPGFQQVIASQSF
YWESQWWADQGFLVVTADNRGTTGRGPSWDREIFEDMKDVTLADQVEAVNALPEAIAKLN
ADRGLSTQLTEGDLAKAENRPSAPCATSRKREAIPMPDLDKVCMIGWSYGGFLSALAVLD
APDVFKAACAGAPPTDWTLYDTHYTERYLGLDPDVYYRNGIVQDAPKLTRPLMLVHGFAD
DNVTIAHSLRLSQALMATGRPHTFLPLTGITHMTNDETVAENLLTLQRDFLREALS