Protein Info for Ac3H11_985 in Acidovorax sp. GW101-3H11

Annotation: Outer membrane vitamin B12 receptor BtuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details PF07715: Plug" amino acids 73 to 178 (106 residues), 99.3 bits, see alignment E=1.8e-32 PF00593: TonB_dep_Rec" amino acids 236 to 603 (368 residues), 108.5 bits, see alignment E=8.2e-35

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 69% identity to aaa:Acav_1577)

Predicted SEED Role

"Outer membrane vitamin B12 receptor BtuB" in subsystem Coenzyme B12 biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JVD1 at UniProt or InterPro

Protein Sequence (630 amino acids)

>Ac3H11_985 Outer membrane vitamin B12 receptor BtuB (Acidovorax sp. GW101-3H11)
MIPMKIRTLRARPVASLRVPAQRLALVALAVGSACSALAQAAPGAGELLAQNLRAPQLGE
TVVAATRTPQPLTDLIADVSIVDRETIETSGATGLADLLARLPGVEFSRNGGPGTTTGVF
LRGAESRFTAVYIDGVRIDSQSTGGAPWESIPLGLIDRIEVLRGPAGAVYGSDAMGGVVQ
IFTKRGENGTAPYVGVGLGSHGTSKLEAGISGASGTLDYALGLSRENSKGFNARTVATQN
PDRDGYRNTAGHARVGLQVDAVHRLEGTLMVNDTNSGYDNGLGKDDRNLHTMHALGLNWN
AQWSSAYKTRLSITDSRDEYETRPSPYLSDTRLRGYYFQNEYRQGAHLVTAALERREDRL
ENQPIDAKRSQDALALGYGYNAAGHTVQLNLRHDSDSEFGGKSTGSAAYGYAITPQWRAT
ASVGTAFRAPTLYHRFSEYGVATLRPESSRNAEVALRYAQGSSTFSATLFRNRVINLISF
GGAGTCASSFGCYANTARAEYKGVTFAGSHRVGDVQLHGSIDLQRPRDLDTGKQLARRAK
QHATFGADTRLAGWTVGAEVQASGRRFDTVANTNVLGGYALVNLYASTRIARDYTLIARI
DNLADKDYQLARTYATAGRVAYVGVKWAPQ