Protein Info for Ac3H11_93 in Acidovorax sp. GW101-3H11

Annotation: Lysophospholipase (EC 3.1.1.5); Monoglyceride lipase (EC 3.1.1.23); putative

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 PF12146: Hydrolase_4" amino acids 45 to 293 (249 residues), 158.9 bits, see alignment E=2.7e-50 PF00561: Abhydrolase_1" amino acids 52 to 160 (109 residues), 40 bits, see alignment E=7.7e-14 PF12697: Abhydrolase_6" amino acids 54 to 297 (244 residues), 45.2 bits, see alignment E=3.8e-15

Best Hits

KEGG orthology group: None (inferred from 81% identity to aaa:Acav_3938)

Predicted SEED Role

"Lysophospholipase (EC 3.1.1.5); Monoglyceride lipase (EC 3.1.1.23); putative" (EC 3.1.1.23, EC 3.1.1.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.23, 3.1.1.5

Use Curated BLAST to search for 3.1.1.23 or 3.1.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165I007 at UniProt or InterPro

Protein Sequence (312 amino acids)

>Ac3H11_93 Lysophospholipase (EC 3.1.1.5); Monoglyceride lipase (EC 3.1.1.23); putative (Acidovorax sp. GW101-3H11)
MAISSWRAGQTPCQNETMSTTTSSFQSNADGTQVTTYTWAQTPGQPVGVVQISHGLAEHG
ERYDRFARALNAAGFIVHAVDHRGHGRTAGGKLGNFGSAGFSGLIADVAQFGALLRAQHG
PQQLPLFLFGHSMGSFAAQAAIIDHSSTWSGVILSGSTTLDLFAAAMANAPADAPAGLAA
FNAGFEHRTGYEWLSRDAAEVDAYVADPWCGWDVPPDVIPSLFAPAPRLADPAQLARIRS
DLPILIASGDADPLAAGGVLLEQLGQRYRDAGVADVAVKLYPAARHEILNETNRDEVTGD
VAAWLRAHTGLA