Protein Info for Ac3H11_896 in Acidovorax sp. GW101-3H11

Annotation: macromolecule metabolism; macromolecule synthesis, modification; dna - replication, repair, restr./modif.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1370 TIGR01967: RNA helicase HrpA" amino acids 31 to 541 (511 residues), 842.5 bits, see alignment E=3.1e-257 PF00270: DEAD" amino acids 46 to 202 (157 residues), 34.9 bits, see alignment E=3.8e-12 PF00271: Helicase_C" amino acids 258 to 379 (122 residues), 41.3 bits, see alignment E=4.8e-14 PF21010: HA2_C" amino acids 470 to 524 (55 residues), 33.7 bits, see alignment (E = 1.3e-11) PF07717: OB_NTP_bind" amino acids 643 to 719 (77 residues), 45.5 bits, see alignment 2.1e-15 PF11898: DUF3418" amino acids 733 to 1367 (635 residues), 714.7 bits, see alignment E=2.9e-218

Best Hits

KEGG orthology group: K03578, ATP-dependent helicase HrpA [EC: 3.6.4.13] (inferred from 86% identity to aaa:Acav_2651)

Predicted SEED Role

"macromolecule metabolism; macromolecule synthesis, modification; dna - replication, repair, restr./modif."

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JV36 at UniProt or InterPro

Protein Sequence (1370 amino acids)

>Ac3H11_896 macromolecule metabolism; macromolecule synthesis, modification; dna - replication, repair, restr./modif. (Acidovorax sp. GW101-3H11)
MRAFMTESAPLSPTPPAPRAAPAAPATTPLRITFPDSLPVSGKREEIMAAITKHQVIIVC
GETGSGKTTQLPKIALALGRGKCNAKPGQKGQLIGHTQPRRIAASSVAKRIAEELNTPLG
DVVGFKVRFQDRLSRDASVKLMTDGILLAETQTDPLLKAYDTIIIDEAHERSLNIDFLLG
YIRQILPRRPDLKVIVTSATIDADRFAKHFESAKGPAPVIMVSGRTFPVEQRWRPFEETR
DHGLNEAIADGVDELWAGNAAGDILIFLPGEREIREAADHLRKHLSHQPVMRNAEVLPLF
ARLSQAEQDRIFDGHTGRRIVLATNVAETSLTVPGVRYVIDAGTARVKRYSFRSKVEQLL
VEPVSQAAANQRAGRCGRVANGICIRLYDEADFNSRPRFTDPEILRSSLAGVILRMKSLH
LGDVGQFPFIEAPSGRAIADGYQLLSELGAVDDANELTPMGVELSKLPLDPRVGRMILEA
RERRALDEVLVIASALSVQDVRDRPLEAQQQADQAHAKFDDEKSEFSGYLKLWKWINEAR
GGAPSLPSARAQKAMAQQKAPSQAHLPVAQRSAAAAPVPAVASVAAPAPTHKLSNRQYEQ
LLRQNFISIRRLREWRDIHTQLLTVVTEHKWQINTQPASYEQIHLSMLSGLLGNIGVKSD
EEDWYLGARGIKFYKHPGAHLSKKPGRWIVAAELVETTRLFGRGIAAIEPQWLEQVGGHL
LKKQMLDPHWEKKAAQVTALERATLYGIVVYNNRRVDFGKVDPQGAREVFLREALVGGEW
ETRLPFLAANQKLIAKVEELEHKSRRQDVLVDDELIYAFYDQQVPQDVCSGTTFERWYKD
ASRANPELLKLTRDELMRHEAAGITTSAFPKTVRLGGVDCTATYLHEPGDARDGITVTIP
LFVLNQVSDERCEWLVPGMLKDKIQALLKSLHQRPRSRFVPLPESAARLAELFNAPERFG
TGSLTDALLKQVRDETSLDVKRADFKLDMLSPHLFMNFRVVDEHGRQLGHGRNLGALKAE
WGAKARGAFQALAGLKLGGAAAEEQKSESKMPSARDGKAQAAIKSGANSPAQPAQPSPAA
QATPSAPAGQRFTSWTFGELPELMEIKKAGQTLIGFPALIDGGDAVSIEVFDEPEVAAAK
HRAGLRRLFALQIKDALKYLEKNIPDLQKMAVAYMPLGTQEELRTQIIDVALDRAFLLDP
LPTDEYAFKRRVEEGRGRLTLIANEVARLAGTILIEYAAAARKIKDTKNAPDATADALQQ
LQRLVPKQFIAQAPWGQLAHFPRYLKAITLRLDKVRADPARDAAKLAELRPQEQRYWRLV
AERKGAVDARMQELRWLLEELRVSFFAQELRTPQPVSVKRLDKLWAQVNS