Protein Info for Ac3H11_740 in Acidovorax sp. GW101-3H11

Annotation: Aspartate ammonia-lyase (EC 4.3.1.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02231: conserved hypothetical protein
  • amino acids 44 to 558 (515 residues), 244.4 bits, E=1.2e-76
• PF13600: DUF4140
  • amino acids 48 to 137 (90 residues), 53.5 bits, E=2.7e-18
• PF13598: DUF4139
  • amino acids 234 to 555 (322 residues), 189.7 bits, E=5.6e-60

Best Hits

KEGG orthology group: None (inferred from 55% identity to vap:Vapar_3625)

Predicted SEED Role

"Aspartate ammonia-lyase (EC 4.3.1.1)" in subsystem Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 4.3.1.1)

MetaCyc Pathways

• L-glutamate degradation II (2/2 steps found)
• superpathway of L-aspartate and L-asparagine biosynthesis (3/4 steps found)
• L-aspartate degradation II (aerobic) (2/3 steps found)
• L-aspartate degradation III (anaerobic) (2/3 steps found)
• L-canavanine degradation II (1/6 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Nitrogen metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.3.1.1

Sequence Analysis Tools

See A0A165JEZ8 at UniProt or InterPro

Protein Sequence (563 amino acids)

>Ac3H11_740 Aspartate ammonia-lyase (EC 4.3.1.1) (Acidovorax sp. GW101-3H11)
MRPVSPPFLPLLRTPLALLQALVMAGLAGLAALPATVHAQDSSRIARVTVYPGSATVERV
AKVAAGARSLRLACLPASLDVQSLQINADPAVRVGEFNVLTEDRDVAAGCASPLDGRIRE
LEDQIAGVKAEASALQLVDGYLRSVAHAGTGEEAATAAGARAASPTPAQITATAEVLRKS
GQDSFARAHQLQRKQEALELALKPLVAERDRVASQRARVVSVTINLAAEREAELRLSYQV
RGPGWQPSYRATLDATKATVLIERQALVAQNSGEDWSGVQLTLSTGQPGRATQGQLPRPW
WLNVAPPPQGAGTQMGMVAMASAPAPAMAPLPRSRNAAEEAMPTFDVSALDKGFATEFAV
PQRITVPSSGQRVTLALGNHTAPATLLTRAAPAVEEAAYLVAQIAQPPGVWPAGAAGLYR
DGAFVGNGRIDFGAPSAGAPAGSTSLSFGRDELVTVRAEPEQDVTGSSGFVGSRVERKTR
RAYSVXNRHKTGITLQLLHAAPVSRNEKIEVESRYQPQPTDLAWNRSAGTIAWQPPLAAG
ATAQFSAEHTVRYPKDIELLERR