Protein Info for Ac3H11_715 in Acidovorax sp. GW101-3H11

Annotation: Transcriptional regulator, LysR family, in glycolate utilization operon

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 PF00126: HTH_1" amino acids 4 to 62 (59 residues), 56.8 bits, see alignment E=1.7e-19 PF03466: LysR_substrate" amino acids 91 to 297 (207 residues), 136.4 bits, see alignment E=8.9e-44

Best Hits

KEGG orthology group: None (inferred from 91% identity to adk:Alide2_4445)

Predicted SEED Role

"Transcriptional regulator, LysR family, in glycolate utilization operon" in subsystem Glycolate, glyoxylate interconversions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JAW2 at UniProt or InterPro

Protein Sequence (310 amino acids)

>Ac3H11_715 Transcriptional regulator, LysR family, in glycolate utilization operon (Acidovorax sp. GW101-3H11)
MDKLKAFESFVSVATRGSLTAAAKAEGVAPAIMGRRLDALEEHLGVKLLVRTTRRISLTH
EGSAFLEDCQRLLSDVANAEASVSEGGVKATGHLRITAPAGFGRRHVAPLVPRFRSAHPD
VTISLNLSDRVVDLAGEGFDCAVRVGDLPDSSLVSVRIADNRRLCVATPEYLARRGTPRA
PAELVQHDCLTLSSDASQTRGWAFRVPHADGSTEVMHLKPGGPLDCSDGQVLHDWCLGGW
GIAWRSTWEVEAEIAAGRLVAVLEDFAAPPNGIYVVFPQRKHLPLRVRLWIEHLKHQYAQ
PAFWKGPQAG