Protein Info for Ac3H11_537 in Acidovorax sp. GW101-3H11

Annotation: [Protein-PII] uridylyltransferase (EC 2.7.7.59)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 866 TIGR01693: protein-P-II uridylyltransferase" amino acids 26 to 859 (834 residues), 774.4 bits, see alignment E=8.2e-237 PF08335: GlnD_UR_UTase" amino acids 168 to 313 (146 residues), 128.3 bits, see alignment E=3.2e-41 PF01966: HD" amino acids 451 to 543 (93 residues), 35.6 bits, see alignment E=1.5e-12

Best Hits

Swiss-Prot: 62% identical to GLND_CUPNJ: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Cupriavidus necator (strain JMP 134 / LMG 1197)

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 90% identity to vei:Veis_3611)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LJ87 at UniProt or InterPro

Protein Sequence (866 amino acids)

>Ac3H11_537 [Protein-PII] uridylyltransferase (EC 2.7.7.59) (Acidovorax sp. GW101-3H11)
MTELHALRDAYRSDKAALLAAMKATGASTRGIRVVLRKLSSLAGSLLQTLWQRAQLPDDL
ALVAVGGFGRDQLFPYSDVDVLLLLPDGAAPEAGSALRAQLEGFIGSCWDTGLEIGSSVR
TVAECLAESAGDVTVQTSLLESRLVCGNAALFAEFQRQYRAQMNPEAFLVAKTLEMRQRH
TKYENTPYSLEPNCKESPGGLRDLQMILWVAQAAGLGRNWKELAASGMATAFEVRQIERN
EALLCLIRARLHAAAGRHEDRLVFDLQTAVAESFGYRSQAPDGSRLPMRASESLMRRYYW
AAKAVSQLSQILLLNIEERLSPSTHEPRPINERFFEKAGLIEVASDDLYTRDPHTILETF
LLYQTTVGLKDLSARTLRALYNARGVMDSAFRRDPVNRDAFMRILQQPSGITHAMRLMNQ
TSVLGRYLWPFRRIVGQMQHDLFHVYTVDQHILMVLRNVRRFFMAEHAHEYPFCSQLAAG
WDKPWILYVAALFHDIGKGRGGDHSQIGAEEVRRFCRQHGVGREDARLIEFLVREHLTMS
TVAQKQDLSDPDVIGAFARRVGNERNLTAMYLLTVADIRGTSPKVWNAWKGKLLEDLYRA
TLRTLGGRAPDAAAEIEARKREALVLLALNALPFEAHKALWATLDVSYFMRHDAADIAWH
TRHLSRHVGTAKPVVRARQSLAGDGLQVMVYAADQADLFARICGYFDRVGFSILDARVHT
ANNGYALDTFQVVASSASEQPGHYRELTHMVESDLMRVIEEGGPLPEPARKRVSRRVKSF
PVAPRVTLRPDEKAQRWLLAISASDRAGLLYLVARILAQHHLSVQLAKVSTLGERVEDTF
LIQGPELQNNARQIQIETELLRELSS