Protein Info for Ac3H11_5010 in Acidovorax sp. GW101-3H11

Annotation: RNA polymerase sigma-70 factor, ECF subfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 PF04542: Sigma70_r2" amino acids 27 to 85 (59 residues), 43.6 bits, see alignment E=3.1e-15 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 28 to 180 (153 residues), 51.5 bits, see alignment E=4.4e-18 PF08281: Sigma70_r4_2" amino acids 129 to 180 (52 residues), 43.4 bits, see alignment 3.3e-15 PF20239: DUF6596" amino acids 198 to 298 (101 residues), 122.6 bits, see alignment E=1.1e-39

Best Hits

KEGG orthology group: None (inferred from 75% identity to bpy:Bphyt_7116)

Predicted SEED Role

"RNA polymerase sigma-70 factor, ECF subfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JK80 at UniProt or InterPro

Protein Sequence (430 amino acids)

>Ac3H11_5010 RNA polymerase sigma-70 factor, ECF subfamily (Acidovorax sp. GW101-3H11)
MHESALPDRDALHRSIDSVWRIEAARIIASVARMTRDVGRAEELAQDALLAALEHWPTTG
LPANPAAWLMTTAKRRAIDHLRQQALHQRENEALGHDLEALEAQYAPDVVETLMHAEQDD
IGDDLLRLIFTACHPVLPTEARVALTLRLLGGLTTAEIARAFLVPEPTVAQRIVRAKRSL
TAAHVPFELPGAAERAPRLASVLEVIYLIFKEGYAATAGDDWMRPALCGEAQRLVRVLAS
LAPDEPEVQGLVALLEIQASRLPARTDAQGQPVLLMDQDRARWDQLLVRRGLAALDKAEQ
LARAGHAWGPYALQGAIAACHARARQAQDTDWPHIVALYDALLQVAPSPVVALNRAVAVG
MAEGPEAALALVDALTDDPLLRHYHWLPSVRGDLLAKLGRGKEARAEFERAAGLTRNAQE
KALLLARACG