Protein Info for Ac3H11_4972 in Acidovorax sp. GW101-3H11

Annotation: Permeases of the major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 412 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 58 to 82 (25 residues), see Phobius details amino acids 91 to 114 (24 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 152 to 174 (23 residues), see Phobius details amino acids 186 to 205 (20 residues), see Phobius details amino acids 240 to 261 (22 residues), see Phobius details amino acids 268 to 290 (23 residues), see Phobius details amino acids 302 to 321 (20 residues), see Phobius details amino acids 327 to 347 (21 residues), see Phobius details amino acids 354 to 382 (29 residues), see Phobius details amino acids 388 to 407 (20 residues), see Phobius details PF07690: MFS_1" amino acids 32 to 375 (344 residues), 72.3 bits, see alignment E=3.7e-24 PF06779: MFS_4" amino acids 33 to 405 (373 residues), 198.7 bits, see alignment E=1.9e-62

Best Hits

KEGG orthology group: None (inferred from 69% identity to vpe:Varpa_3157)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JIR1 at UniProt or InterPro

Protein Sequence (412 amino acids)

>Ac3H11_4972 Permeases of the major facilitator superfamily (Acidovorax sp. GW101-3H11)
MPTRPAPVDVSAASSAAPIPTLWLAVALSMGAAISLGITRFSYALLLPPMREDLGWSYTL
AGGMNTANALGYLLGALATPLLLRRVAPGRVLLVGAVLASVFMGLSGFFTAAPWLLLQRL
LAGVASALVFIAGGLLAARLGAHAPGRSGLLLGLYYGGTGWGISLSALLVPGVLAAAGPV
PHPWAWAWWALALACVAATAVLWWPAQALQVLAPPSASPTAFNITPPPATVRWRALAPAL
LGYGLFGVGYIGYMTFVVALLREQGASGGAITAFYALLGLAVVLSSRIWAGLLDRSRGGE
ALARLNALLGLATVLPALTGAWPVVLASGLLFGGVFLSVVASTTALVRHNLPQALWASGI
SAFTIVFAAGQIVGPTVVGWIADGPGGLARGLVFSACALWVGALVAWRQKPL