Protein Info for Ac3H11_4965 in Acidovorax sp. GW101-3H11

Annotation: RNA polymerase ECF-type sigma factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 12 to 174 (163 residues), 58 bits, see alignment E=8.8e-20 TIGR02957: RNA polymerase sigma-70 factor, TIGR02957 family" amino acids 12 to 298 (287 residues), 331.1 bits, see alignment E=4.9e-103 PF04542: Sigma70_r2" amino acids 13 to 75 (63 residues), 52.2 bits, see alignment E=4.2e-18 PF08281: Sigma70_r4_2" amino acids 120 to 169 (50 residues), 50.8 bits, see alignment 1e-17

Best Hits

KEGG orthology group: K03088, RNA polymerase sigma-70 factor, ECF subfamily (inferred from 69% identity to bpr:GBP346_A1239)

Predicted SEED Role

"RNA polymerase ECF-type sigma factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JIL6 at UniProt or InterPro

Protein Sequence (303 amino acids)

>Ac3H11_4965 RNA polymerase ECF-type sigma factor (Acidovorax sp. GW101-3H11)
MTLSAPAPADPFTTLRPRLFGIAYRMLGVRADAEDVLQDAWLRWSRQDPTALQSAEAWLV
TVVTRLSIDRLRALKAEREAYVGWWLPEPLVQLHDPSTGDAQHHHTPEAAAELAGELSVA
FMYVLERLGPEERAAFLLRQVFDYDYPEIAAQLGKTEAACRQMVHRASERVQQARTRFEV
PRAVHHQLLQRFMQAAHSGDRSAIEALLSEDAQLIGDGGGKVPSFPKPLVGPFRIANLYW
ALFRRLGAQVVYRMALINGEPGLLRYVDGRIESAQALVTDGERIVAIYAVRNPDKLAGVP
ATL