Protein Info for Ac3H11_4906 in Acidovorax sp. GW101-3H11

Annotation: putative carboxylesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 509 PF00135: COesterase" amino acids 8 to 471 (464 residues), 294.6 bits, see alignment E=2.7e-91 PF07859: Abhydrolase_3" amino acids 166 to 231 (66 residues), 27.9 bits, see alignment E=2.8e-10

Best Hits

Predicted SEED Role

"putative carboxylesterase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JH36 at UniProt or InterPro

Protein Sequence (509 amino acids)

>Ac3H11_4906 putative carboxylesterase (Acidovorax sp. GW101-3H11)
MTVGTAAPQVTLPHGGQLRGLWEQGVRVFRGVRYAQAPSGTLRFAAPVPASPWLGVRNAT
EFAPMAPQLPRTARADASMLGGDDCLAVNVWAPPAEPGACLPVMVWVHGGGFFRGAASEP
LYDGASFARQGVVFVSLQYRLGIDGFLHFEDEGEAGSRGGAAPANRGLLDLLAALQWVRE
HISAWGGDPAQVTVFGQSAGAGALACVLGMPASRGLLLRAILQSPSVACQTLQEAAAARR
AVAALVGVAPSLAALGAAARPAVLHAVHRLAADPALRQQHGLGIRNFFPLRPVVDGQVLV
APPLQALAQQWAAHPPDLQVLVGSNAEEMRLYHVPGGAMDRVTEAQVLAFAQEVGLGADA
VQALRTTLPPTPPTPGELLCALQSDFYYRVPAQRIAALASRWARSAHAYEFAWPSPQWRG
RLGAAHGVELPFVFGNLHTATGQELTGPRPPTALAATMHQGWVAFAQWGDPGWAPYAGVQ
PLVQRFGVASPACAPHPEPARFSLWDGLL