Protein Info for Ac3H11_4751 in Acidovorax sp. GW101-3H11

Annotation: Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 transmembrane" amino acids 52 to 77 (26 residues), see Phobius details amino acids 102 to 126 (25 residues), see Phobius details amino acids 137 to 159 (23 residues), see Phobius details amino acids 166 to 190 (25 residues), see Phobius details amino acids 204 to 226 (23 residues), see Phobius details amino acids 268 to 286 (19 residues), see Phobius details amino acids 329 to 347 (19 residues), see Phobius details amino acids 353 to 372 (20 residues), see Phobius details amino acids 377 to 398 (22 residues), see Phobius details amino acids 410 to 430 (21 residues), see Phobius details amino acids 440 to 459 (20 residues), see Phobius details PF00033: Cytochrome_B" amino acids 43 to 230 (188 residues), 225.7 bits, see alignment E=6.7e-71 PF13631: Cytochrom_B_N_2" amino acids 113 to 286 (174 residues), 149 bits, see alignment E=2e-47 PF00032: Cytochrom_B_C" amino acids 300 to 340 (41 residues), 48.5 bits, see alignment 1.4e-16 amino acids 366 to 449 (84 residues), 79.2 bits, see alignment E=3.8e-26

Best Hits

KEGG orthology group: K00412, ubiquinol-cytochrome c reductase cytochrome b subunit [EC: 1.10.2.2] (inferred from 91% identity to vei:Veis_3934)

Predicted SEED Role

"Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2)" in subsystem Ubiquinone Menaquinone-cytochrome c reductase complexes (EC 1.10.2.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.10.2.2

Use Curated BLAST to search for 1.10.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LA95 at UniProt or InterPro

Protein Sequence (476 amino acids)

>Ac3H11_4751 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) (Acidovorax sp. GW101-3H11)
LKEHDDMAEFKEISPNASAGAKVTNWFENRFPTAFDAYKVHMSEYYAPKNFNFWYIFGSL
ALVVLVIQIVTGIFLVMHYKPDANLAFASVEYIMRDVPWGWLIRYMHSTGASAFFVVVYL
HMFRGLIYGSYRKPRELVWIFGCAIFLCLMAEAFMGYLLPWGQMSYWGAQVIVNLFAAIP
FIGPDLALLIRGDYVVGDATLNRFFSFHVIAVPLVLLGLVVAHLLALHDVGSNNPDGVEI
KGPKAPKDANGKPLDGVPFHPYYTVHDIFALSMFLMAFTAVVFFAPEFGGYFLEYNNFIP
ADPLKTPAHIAPVWYFTPFYSMLRAITTEMMYALILCVVAGAGFGVLKAKLPSFIKAGVV
GVALVVVAMMLSIDAKFWGVVVMGGAVIILFFLPWLDYSPVKSIRYRPDWHKYLYGIFVI
NFLILGYLGVQPPSPIGERVSQVGTLFYFGFFLLMPWWSRIGETKPVPDRVTFVAH