Protein Info for Ac3H11_4675 in Acidovorax sp. GW101-3H11

Annotation: Two-component sensor PilS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 509 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 228 to 250 (23 residues), see Phobius details PF00512: HisKA" amino acids 274 to 337 (64 residues), 33.6 bits, see alignment E=3.4e-12 PF02518: HATPase_c" amino acids 389 to 499 (111 residues), 69.1 bits, see alignment E=4.5e-23

Best Hits

KEGG orthology group: None (inferred from 56% identity to vpe:Varpa_2940)

Predicted SEED Role

"Two-component sensor PilS" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LRV6 at UniProt or InterPro

Protein Sequence (509 amino acids)

>Ac3H11_4675 Two-component sensor PilS (Acidovorax sp. GW101-3H11)
LRHTPHLPSLVVWALVACAGCSWLVLNRLQQLHAAFETDARIVHRLLSQRVVQHDAILAT
LALLQPTAPRQGSAADATLPRLPSVYPQILSVLQRPGGAGEGSERGWPGALQAPLSAAEA
ASRRSGHAEMALVDLPAGRFHLVLASTPASHALQIDLRATVPQDEWPMDMATSPVRVTLE
QGGAAFVVQPGRADEGLGWSYAFHKLLAAPSQPLDVVARRTVGIAELPWLAMLGWCMFTA
ALWGGGLAWWRQRIARQRAEELLRLGQVARLNTLGELAAGMAHELNQPLTALLSSTQAAQ
RLLADDPPDLDTAQTAMARAVEQARRASTVVGRLRRLVERPDLAGQAQPLALATAVQDVL
HLLEPEMAQRGVAPTVSIAPDLPAVLAEPVALQQIVHNLLMNALQALDQVPPAERQLVLR
LWMPDAAHAALSVRDHGPGVPPEARAHLFEPFYTTRTGGLGLGLTLCESLAQAMGASLAL
APADPAVRGAEFLLVLPAAPDTPSPSSVL