Protein Info for Ac3H11_4669 in Acidovorax sp. GW101-3H11

Annotation: AMP nucleosidase (EC 3.2.2.4)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 493 TIGR01717: AMP nucleosidase" amino acids 17 to 493 (477 residues), 658.1 bits, see alignment E=4.2e-202 PF10423: AMNp_N" amino acids 19 to 172 (154 residues), 188.6 bits, see alignment E=5.6e-60 PF01048: PNP_UDP_1" amino acids 278 to 440 (163 residues), 54.8 bits, see alignment E=8.9e-19

Best Hits

KEGG orthology group: K01241, AMP nucleosidase [EC: 3.2.2.4] (inferred from 93% identity to vei:Veis_1155)

Predicted SEED Role

"AMP nucleosidase (EC 3.2.2.4)" in subsystem Purine conversions (EC 3.2.2.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.2.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LRR3 at UniProt or InterPro

Protein Sequence (493 amino acids)

>Ac3H11_4669 AMP nucleosidase (EC 3.2.2.4) (Acidovorax sp. GW101-3H11)
MPLIPDFIAPTRHTDPADALAQVQRIYQQQIGHLRDAMQRFVAGETPEGPVRAFYPFVRV
HTTTVARADTKLAYGFVEGPGRYETTLTRPDLFANYYAEQFRLLRASHNVELEVGTSTHP
IPIHFSFAEHDHIEGTLTPARRMLMRDVFDLPDLAAMDDGIANGTWQAAPGEAQPLSLFT
APRVDYSLHRLRHYTGTAPEWFQNFVLFTNYQFYIDEFVRLGHAEMAKPDSEYIAFIEPG
NVVTRRVGLSAEAGDDLGAAPPRLPQMPAYHLVRKDASGISMVNIGVGPANAKTITDHIA
VLRPHAWMMLGHCAGLRNSQQLGDYVLAHAYVREDHVLDEDLPLWVPIPALAEIQLALQQ
AVADVTQIGGADLKRVMRTGTVASTDNRNWELLPDNTPQRRFSQSRAVALDMESATIAAN
GFRFRVPYGTLLCVSDKPLHGEIKLPGMANHFYRERVDQHLRIGMRAIEILRNGGVDRLH
SRKLRSFAEVAFQ