Protein Info for Ac3H11_4575 in Acidovorax sp. GW101-3H11

Annotation: Permease of the drug/metabolite transporter (DMT) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 40 to 61 (22 residues), see Phobius details amino acids 74 to 95 (22 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 130 to 149 (20 residues), see Phobius details amino acids 156 to 175 (20 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details amino acids 213 to 235 (23 residues), see Phobius details amino acids 246 to 264 (19 residues), see Phobius details amino acids 270 to 288 (19 residues), see Phobius details amino acids 295 to 312 (18 residues), see Phobius details amino acids 318 to 336 (19 residues), see Phobius details PF00892: EamA" amino acids 12 to 142 (131 residues), 49.8 bits, see alignment E=2.3e-17 amino acids 157 to 288 (132 residues), 36.7 bits, see alignment E=2.5e-13

Best Hits

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LPQ7 at UniProt or InterPro

Protein Sequence (398 amino acids)

>Ac3H11_4575 Permease of the drug/metabolite transporter (DMT) superfamily (Acidovorax sp. GW101-3H11)
MARGSLSLPALRGGLLALLAAALFGISTPLVQRLGAGLGAFTTAALLYAGAAVVGALSLR
TAAHEARLQRSDAWRLIGMAGFGAALGPVALSWGLQHTSGASASLMLTLEALFTATLAWW
LYSETMDRRVWAAMLLLLAGGMALVMDQGLQGGTQLLGLLAVLLATVAWGVDNTLSRGLA
ERDPSQVVMAKASLGAAATACLAMAWGEPLPTLTAALGLFAVGATGYGLSLRFYLLAQRA
FGAARTGSVFAFAPFIGAAVAFGFGERSAGWLMLLGGLLMLAGVLLAFGAARTGSVFAFA
PFIGAAVAFGFGERSAGWLMLLGGLLMLAGVLLHLAESHGHEHAHDPLEHEHAHRHDDGH
HTHSHDVMPTGSHSHVHFHEPVTHAHPHAPDVHHQHRH