Protein Info for Ac3H11_4411 in Acidovorax sp. GW101-3H11

Annotation: Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 PF02481: DNA_processg_A" amino acids 85 to 297 (213 residues), 241.3 bits, see alignment E=6.3e-76 TIGR00732: DNA protecting protein DprA" amino acids 86 to 306 (221 residues), 240.2 bits, see alignment E=7.5e-76 PF17782: DprA_WH" amino acids 330 to 384 (55 residues), 70.5 bits, see alignment 9.8e-24

Best Hits

KEGG orthology group: K04096, DNA processing protein (inferred from 68% identity to aav:Aave_4686)

Predicted SEED Role

"Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165K5H6 at UniProt or InterPro

Protein Sequence (392 amino acids)

>Ac3H11_4411 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake (Acidovorax sp. GW101-3H11)
MDHEELGAWLRLTLSPGVGNGTARRLLSRFGLPQAIFQQPEAALQQCVTNAQARALCEIP
AAWQALWDTTAQWLSGAGPEGPARTIVTLGDVRYPQSLLDTEDPPLLLYLTGPAQLLAHQ
PFPSDRCLAVVGSRNPTAQGAENARLFSRALHGAGLTIVSGLALGVDAAAHEGALDASVA
GAPAAATIAVVGTGLDRVYPRKNLDLARRIAARGLLVSEYPLGTPPLAANFPKRNRIISG
LSQGTLVVEAALASGSLITARMAVEQGREVFAIPGSIHAPQSRGCHALIRQGAKLVESAQ
DVLEELRLPTTTVPGLPEEHAEEGAAVEERAESGSDSNPVLAALGFDPLGLDALVARTGM
DTAALQVMLLELELDGRVARLPGGLFQRLGRG