Protein Info for Ac3H11_4080 in Acidovorax sp. GW101-3H11

Annotation: integral membrane sensor signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 613 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 31 to 47 (17 residues), see Phobius details amino acids 62 to 84 (23 residues), see Phobius details amino acids 93 to 115 (23 residues), see Phobius details amino acids 133 to 155 (23 residues), see Phobius details amino acids 168 to 189 (22 residues), see Phobius details amino acids 198 to 218 (21 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details amino acids 254 to 271 (18 residues), see Phobius details PF00512: HisKA" amino acids 403 to 454 (52 residues), 34.5 bits, see alignment 1.7e-12 PF02518: HATPase_c" amino acids 494 to 609 (116 residues), 66.9 bits, see alignment E=2.1e-22

Best Hits

Predicted SEED Role

"integral membrane sensor signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165M0B0 at UniProt or InterPro

Protein Sequence (613 amino acids)

>Ac3H11_4080 integral membrane sensor signal transduction histidine kinase (Acidovorax sp. GW101-3H11)
MLIHAVLGFSVLETLVLAALLLAWADRVAGARLLAAFLTGISLWMVGNELPNWVGPATEP
VAMRLLATAPFTSALFFHFCTVFCRVDLGRWGVAAAYALGGGASVVSILLVPGHLIHHRD
IGWLAVADPVGMVASMAWVILGIGGVWVLLHALLRARRLGDGQKFRQIAAVTASCLWGLL
CLAGYGIAVLDLPVYPFPLLGLPFYSLILVYGILRYGVFVANAWARRALVWALLLALGLV
VVALTPLLPLESRWLGGLAVAASVLALNGPVRRVAERLVYPGADVSAADLATWRRTLGSA
ETPQALGEQAAALLSARTGTQVEVHIGDAPPAASSTPQLVCGRASEGWAVSLQGWDAAPP
GPRHVAELFGTVVAEAAERVEQAQQFAARERERQLQARLAELGALAATVAHDIRNPLNII
SMAVAAAPSDTRREVAEQVARIAHLTHDLLDFAKPWKLAPSTIDLAAQVRNAALRLPDVS
FGPGLSEPLWLQADPRRVDQALTNLFENARMATAPANDAEGPAAARTHSHVHIDAETTAT
TVLLHVCDAGPGVPAEIRDRLFEPFASRSPGGTGLGLAIVARTMAAHGGAVALTERAPWS
TCFTLSFPRSSAP