Protein Info for Ac3H11_392 in Acidovorax sp. GW101-3H11

Annotation: diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 240 to 262 (23 residues), see Phobius details PF12792: CSS-motif" amino acids 38 to 239 (202 residues), 83.4 bits, see alignment E=1.6e-27 PF00563: EAL" amino acids 271 to 502 (232 residues), 206.2 bits, see alignment E=5.3e-65

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LG82 at UniProt or InterPro

Protein Sequence (522 amino acids)

>Ac3H11_392 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (Acidovorax sp. GW101-3H11)
MKRFYVVASIPLLLAALIPIAASLWVAHRKAKDDQITYLTSLADEALRRGVASRQQLVAA
LNELDRDPHPPCSQASLTRMQQLVGTSFYLQGMGSVMNGTLVCSTLTQGSDLVPLTGNHM
VTSTGIASWIGARLPFAPDQPFNIYARNGHAVIIHPGIVIDMPVLHDDVSLGLLISAPQA
LIRSKGPLDAQWLALYTPHASSQVESDTHHIVFRASKDNNIAAIAAAPKAQAYGGLRAQA
LILAPLGLVASALFALGVAMLTRWQLSPRVRLRAALRRREFFILYQPIVDLQTGQWVGAE
ALLRWRRRNGTLVPPDEFIAEAEKAGVIASITRYVMDMVLADLPELLKASPGFHVSLNLS
PQDLVADGPVQYLQRRFSAMEFPAGALMLEVTERGLVDIEAARPALQAARQIGASIALDD
FGTGYSSLSMLESIDIDTLKIDRIFIASIGAQAAISPVTTHIIEMAHTLKLALIAEGVET
QDQVDFLIARGVRQAQGWKFARAMPLVELLAGLRAAPAARQR