Protein Info for Ac3H11_369 in Acidovorax sp. GW101-3H11

Annotation: CAIB/BAIF family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 46% identical to SCCT_CHLAA: Succinyl-CoA--D-citramalate CoA-transferase (Caur_2266) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)

KEGG orthology group: K07749, formyl-CoA transferase [EC: 2.8.3.16] (inferred from 87% identity to ctt:CtCNB1_1671)

MetaCyc: 43% identical to succinyl CoA:L-malate CoA transferase beta subunit (Chloroflexus aurantiacus)
2.8.3.7-RXN [EC: 2.8.3.22]; 2.8.3.22 [EC: 2.8.3.22]

Predicted SEED Role

"CAIB/BAIF family protein"

MetaCyc Pathways

oxalate degradation II (1/3 steps found)
3-hydroxypropanoate cycle (8/13 steps found)
superpathway of the 3-hydroxypropanoate cycle (8/18 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.8.3.16 or 2.8.3.22

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LJT7 at UniProt or InterPro

Protein Sequence (436 amino acids)

>Ac3H11_369 CAIB/BAIF family protein (Acidovorax sp. GW101-3H11)
MLDCDGGLLLERFAGGRRVRIIAPQHYRLHETNRSMDSTASPAALQGVRVIEMGQLIAGP
FCGKTLGEFGADVIKIEAPETGDPLRNWRLIKGGTSVWWQVQSRNKRSVALDLRQKEGQA
IARQLIAEADVLVENFRPGTLEGWGMSPDELHALNPGLVILRISGYGQTGPYRDLPGFGV
IGEAMGGLRHLTAEPGRVPVRVGVSIGDTLAALHGTIGVLTALYHRKVNGGKGQVIDVAL
HEAVFNVMESLIPEYSAFGAVREAAGSALPGIAPSNAYPCQDGWVLVAGNGDSIFKRLMT
AIGRQDLADAPDLGSNTGRVARVGEIDTAIGAWTAARSVQQVMETLGAARVPAGKVYTAK
DIAEDPHYRARDMLLTQETRDGYSVEVPGIVPKLSGTPGSIRRSAPHLGDDTDAVLAEAG
LTAEQIALLRSKGVIQ