Protein Info for Ac3H11_3354 in Acidovorax sp. GW101-3H11

Annotation: Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 transmembrane" amino acids 210 to 231 (22 residues), see Phobius details PF00005: ABC_tran" amino acids 28 to 167 (140 residues), 93.3 bits, see alignment E=2.1e-30

Best Hits

Swiss-Prot: 38% identical to HMUV_GLOVI: Hemin import ATP-binding protein HmuV (hmuV) from Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)

KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 61% identity to maq:Maqu_3529)

Predicted SEED Role

"Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3)" in subsystem Iron acquisition in Vibrio (TC 3.A.1.14.3)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.34

Use Curated BLAST to search for 3.6.3.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KFV2 at UniProt or InterPro

Protein Sequence (260 amino acids)

>Ac3H11_3354 Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3) (Acidovorax sp. GW101-3H11)
MKDGLQIDQLTAGYPGRPVLQGVTLPGVPAGTLVAVVGPNAVGKSTLLKAVAGLRPAQGR
VWLEGTDLATLAPRERLRRVGYLPQALPQSTSLVAYETWQSALRASRSEWSTAQREAAIE
SVVATLGLQALALRRLDELSGGQRQMVGLAQVIVRAPRLLLLDEPTSALDLRWQLQVLQA
VRALVLQQGAIGLVAVHDLNLALRFCQHVLVLGGGSVLAAGAPATVLTPALLQRAYGVLA
RVERCSEGHLLVLADAALPQ