Protein Info for Ac3H11_3332 in Acidovorax sp. GW101-3H11

Annotation: Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 646 transmembrane" amino acids 18 to 39 (22 residues), see Phobius details TIGR03423: penicillin-binding protein 2" amino acids 17 to 611 (595 residues), 743.3 bits, see alignment E=1e-227 PF03717: PBP_dimer" amino acids 61 to 236 (176 residues), 148.7 bits, see alignment E=2.5e-47 PF00905: Transpeptidase" amino acids 268 to 606 (339 residues), 225.6 bits, see alignment E=8.3e-71

Best Hits

KEGG orthology group: K05515, penicillin-binding protein 2 (inferred from 83% identity to vei:Veis_1607)

Predicted SEED Role

"Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129)" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Flagellum in Campylobacter or Peptidoglycan Biosynthesis (EC 2.4.1.129)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KFC2 at UniProt or InterPro

Protein Sequence (646 amino acids)

>Ac3H11_3332 Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) (Acidovorax sp. GW101-3H11)
MTELRSSEADASRFRLRAVVVGLVVFAAFCLVVARLIFLQVVRHDDLAAQAESNRTAVAP
IVPNRGLILDRNGVVLATNYSAYTLEITPSRAGVLDETIDALSKVVDIQARDRRRFKRLM
DESRNFESLPIRTRLTDQEVARFTAQRYRFPGVDIKARLFRNYPLGDVGAHAIGYIGRIN
QTEKARIQDSEDEANYRGTEYIGKLGVEQSFEAALHGVTGFEQMETSAGGRAVRKLSSHA
ATPGDSVMLSIDIKLQKLIEELYGSRRGALVVIDPRNGEILALVSKPTFDPNLFVEGIDA
ENWAALNESIDKPLLNRALRGTYPPGSTYKPFMALAALQLNKRSPSLVVNDPGFYTFGGH
TFRSHEGGLGGVDMHRAIQQSSNTYFYSLAVDMGVDAIHDFMKPLGFGQSTGIDLNGEVR
GTLPSTEWKRNAYKRPEMKRWFPGETVSLGIGQGYNNFTMLQLALAQATMANGGTRYRPH
LAKAVKNSVTGAITEIVQPPGENLGYAPKNVEIVRNAMVAVNKGGTGTRVFAGALYTAGG
KTGTAQAVSLGQNVKYNAKALEEHQRDHSLFAAFAPAENPTIAVAAIVENAGFGAAHAAP
IVRRVFDYWLQGEYPSEEDIAAVQKGQAAAPIGKPRKAAEVALPLP