Protein Info for Ac3H11_3315 in Acidovorax sp. GW101-3H11

Annotation: Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 PF01590: GAF" amino acids 20 to 145 (126 residues), 23.9 bits, see alignment E=1.6e-08 PF00158: Sigma54_activat" amino acids 190 to 356 (167 residues), 223.7 bits, see alignment E=3.5e-70 PF14532: Sigma54_activ_2" amino acids 191 to 361 (171 residues), 76.6 bits, see alignment E=6.9e-25 PF07728: AAA_5" amino acids 213 to 334 (122 residues), 39.1 bits, see alignment E=2.3e-13 PF00004: AAA" amino acids 214 to 332 (119 residues), 22.5 bits, see alignment E=4.1e-08

Best Hits

Swiss-Prot: 77% identical to NORR2_CUPNH: Nitric oxide reductase transcription regulator NorR2 (norR2) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

KEGG orthology group: K12266, anaerobic nitric oxide reductase transcription regulator (inferred from 73% identity to cti:RALTA_B2089)

Predicted SEED Role

"Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR" in subsystem Nitrosative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165HHI7 at UniProt or InterPro

Protein Sequence (521 amino acids)

>Ac3H11_3315 Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR (Acidovorax sp. GW101-3H11)
MLHTPLLADLATDLPQAVRLQRLVAHLRDRFHCGAVALLQLEEDHLRPVAVEGLVREALG
RRFAVSQHPRLAAILARTDVTWFHHDSTLPDPYDGLLDTLVGEPLPVHDCMGIRLSVDGQ
PWGVLTLDALQTGTFGDDARAALADCRVLAEAAVRISRLEREVQALRTAPPLRSVDDERT
PRAGDADMEIVGQSEPLMRLLHELDVVAGSDLPVLLLGETGVGKELFARRLHRQSPRAAR
PLVHVNCAALPESLAESELFGHVRGAFSGAVADRPGRFEAAEGGTLFLDEVGELPLAVQA
KLLRTLQNGEIQRLGADRPRRVNVRVIAATNRNLREQVTGGAFRADLYHRLSVYPVPIPP
LRDRGNDVLLIAGRFLELNRARLGLRSLRLSGPAQEALRRYPWPGNIRELEHVVSRAALK
ALSRGVSRADIVTLEPALLDLDADAVRTPATPPDATAQSAGPRAALPAAPTGPLREAVDA
CQRTSITTALAQHGGNWAQAARALEVDASNLHKLARRLGIK