Protein Info for Ac3H11_3279 in Acidovorax sp. GW101-3H11

Annotation: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF12833: HTH_18" amino acids 245 to 322 (78 residues), 69.2 bits, see alignment E=3.1e-23 PF00165: HTH_AraC" amino acids 286 to 322 (37 residues), 33 bits, see alignment 4.8e-12

Best Hits

Predicted SEED Role

"Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165HGQ3 at UniProt or InterPro

Protein Sequence (326 amino acids)

>Ac3H11_3279 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain (Acidovorax sp. GW101-3H11)
MPQPPLPPLRLALLLYPGCMPAGLFATADLARAANLRAQRAVVTTCWAGVDLQPVPTWQG
PALTPGVALAQAEVDAVLVPGLWLSSPDGWQAPALQQQLAPAVAALRAVPRRTRVWSYCA
GVALAAASGRLRGRGATATWWLRAALEQQFGAVHWRFDEPLVEDGPATTAAGANGHLPLM
LHALAQRLDAAALGDLQSLLMLPRPRTTHPAFAEHDLMAVTDPTLRRALLWVQRCPATAL
RLPALAEALALSPRTLARRVQAHTGLSAALWMRRIKLRQVGEALCDTPLPLKRIAEDLGF
ASEAGLHRAFQQATGQTPLAYRMAHG