Protein Info for Ac3H11_3180 in Acidovorax sp. GW101-3H11
Annotation: Benzoylformate decarboxylase (EC 4.1.1.7)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01576, benzoylformate decarboxylase [EC: 4.1.1.7] (inferred from 84% identity to pna:Pnap_1023)Predicted SEED Role
"Benzoylformate decarboxylase (EC 4.1.1.7)" in subsystem Benzoate degradation (EC 4.1.1.7)
MetaCyc Pathways
- D-phenylglycine degradation (1/3 steps found)
- 4-hydroxymandelate degradation (2/6 steps found)
- mandelate degradation I (1/5 steps found)
- indole-3-acetate degradation II (1/7 steps found)
- mandelate degradation to acetyl-CoA (5/18 steps found)
- superpathway of aromatic compound degradation via 3-oxoadipate (14/35 steps found)
- superpathway of aromatic compound degradation via 2-hydroxypentadienoate (12/42 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.1.1.7
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A165IUH6 at UniProt or InterPro
Protein Sequence (532 amino acids)
>Ac3H11_3180 Benzoylformate decarboxylase (EC 4.1.1.7) (Acidovorax sp. GW101-3H11) MPSDATPLPTVREAVLDLLRGFHINTIFGNPGSTELPLFLDFPQDFRYILGLQESVVVGM ADGYAQATHNAAFVNLHSAAGVGHAMGNIFTAHKNRTPMVITAGQQARSILPFDPFLFSG QATELPKPYVKWSIEPARAEDVPLAIARAYYIAMQQPRGPVLVSIPADDWDKPCEPLQAR TVSTESRPEPRVLQAIGDAMDAAQRPVFVVGAAVDRDRAWDDVLALAERHNAAVWIAPMS GRCGFPQDHRLFAGVLPAMREKIVALLGGHDLVFALGAAAFTYHVEGFGPHVPPGAQLVQ LIDDPGTAAWTPEGTSAVGSVRLGVQDLLARPAPIARALPPARAARPRVEASAPGALMSV PYVMQTLAEVRDAASIVVEEAPSARAAMHAYLPILQSETFYTMCSGGLGYGLPAAVGVAL AKPDRKVIGLIGDGSAMYSIQALWSAAQLQLPITFIILKNRRYAALQEFAPTFGFHEGAK LEGTELPDLDFLALARGQGCDAVHVSDASQLAPVLREALAHPRAMLVEVDVA