Protein Info for Ac3H11_3139 in Acidovorax sp. GW101-3H11

Annotation: Putative TolA protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 320 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details TIGR02794: protein TolA" amino acids 20 to 301 (282 residues), 111.2 bits, see alignment E=6.7e-36 PF13103: TonB_2" amino acids 234 to 307 (74 residues), 69.8 bits, see alignment E=8.8e-24 TIGR01352: TonB family C-terminal domain" amino acids 258 to 316 (59 residues), 27.4 bits, see alignment E=3.2e-10

Best Hits

KEGG orthology group: K03646, colicin import membrane protein (inferred from 68% identity to dia:Dtpsy_2263)

Predicted SEED Role

"Putative TolA protein" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165ITR6 at UniProt or InterPro

Protein Sequence (320 amino acids)

>Ac3H11_3139 Putative TolA protein (Acidovorax sp. GW101-3H11)
MQAHTDRDQFAPPRPPARLRAITLAVLVHAVLIGALTWGVNWKNTADQPAVEAELWAAVP
TQAAARAMEPPAPPPPPPTPEPIAPPPPPVRAVQPPDTREAEIAIEREKKRLEQEKKARE
QQQEREKRERERKDEERKDRLEQEKKERLQKEKDKEQREKQLAEQKKAEQDKQKKLAEDK
RKADEAAKRKADAEAKQLAEQREANMRRIQGMAGATGAETATGTAQRSAGPSGAYGGMVS
AKVKPNIVYPDMITGNPRAEVEVRLSPDGTIVGKRLVRPSGNKAWDDAVLRALDKTETLP
RDIGGRAPPASLIIGFSPQD