Protein Info for Ac3H11_3072 in Acidovorax sp. GW101-3H11

Annotation: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01135: glutamine-fructose-6-phosphate transaminase (isomerizing)
  • amino acids 2 to 641 (640 residues), 769.9 bits, E=9.6e-236
• PF13522: GATase_6
  • amino acids 73 to 203 (131 residues), 70.7 bits, E=1.9e-23
• PF13537: GATase_7
  • amino acids 111 to 219 (109 residues), 59.7 bits, E=4.3e-20
• PF01380: SIS
  • amino acids 325 to 445 (121 residues), 87.4 bits, E=1.1e-28
  • amino acids 498 to 621 (124 residues), 72.3 bits, E=5.1e-24

Best Hits

KEGG orthology group: K00820, glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC: 2.6.1.16] (inferred from 87% identity to dia:Dtpsy_0620)

Predicted SEED Role

"Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)" in subsystem Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 2.6.1.16)

MetaCyc Pathways

• O-antigen building blocks biosynthesis (E. coli) (10/11 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis I (5/5 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis II (4/6 steps found)
• chitin biosynthesis (5/9 steps found)
• UDP-N-acetyl-D-galactosamine biosynthesis III (2/6 steps found)
• CMP-legionaminate biosynthesis I (2/10 steps found)
• superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (6/24 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (12/33 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Glutamate metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.16

Sequence Analysis Tools

See A0A165JQY5 at UniProt or InterPro

Protein Sequence (641 amino acids)

>Ac3H11_3072 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (Acidovorax sp. GW101-3H11)
MCGIVGAVSTRNIVPILVQGLQRLEYRGYDSCGVAVHGASIDASRHGTARGGLQRARSTA
RVAELLEQVQAEHVDGATGIAHTRWATHGAPAVHNAHPHFSHGLGVDAATQQAGRVALVH
NGIIENHEELRRTLQARGYVFASQTDTEVIAHLVDSHYSGDLFEAVRATVAELHGAYAIA
VIHKDEPHRVVGARAGSPLILGVGNAGAEHFLASDAMALAGVTDQIVYLEEGDLVDLQLG
RYWIVGKDGAALSPAQRPVRTVQAHSGAAELGPYRHYMQKEIFEQPRAIADTLEGVEGIV
PELFDGAGQHGQPGAAAWRVFKEIDNVLILACGTSYYSGCAAKYWLEEIAGIPTQVEVAS
EYRYRTSVPNPRTLVVTITQSGETADTLAALRHAQSLGMQHTLTICNVVTSAMVRECKLA
YITRAGVEIGVASTKAFTTQLAGLFLLTLALAQSKGRLSEEQEAAHLKAMRHLPVALQAV
LALEPQLISWAEDFARMENALFLGRGLHYPIALEGALKLKEISYIHAEAYPAGELKHGPL
ALVTSAMPVVTVAPNDALLEKLKSNMQEVRARAGVLYVLADGDTHIESSEGIHVIRMPEH
YGALSPLLHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE