Protein Info for Ac3H11_2999 in Acidovorax sp. GW101-3H11

Annotation: Two-component hybrid sensor and regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 614 transmembrane" amino acids 45 to 65 (21 residues), see Phobius details amino acids 71 to 90 (20 residues), see Phobius details amino acids 113 to 133 (21 residues), see Phobius details amino acids 139 to 156 (18 residues), see Phobius details amino acids 164 to 182 (19 residues), see Phobius details amino acids 187 to 204 (18 residues), see Phobius details PF00512: HisKA" amino acids 244 to 308 (65 residues), 34.2 bits, see alignment E=3.2e-12 PF02518: HATPase_c" amino acids 355 to 464 (110 residues), 76.1 bits, see alignment E=4.5e-25 PF00072: Response_reg" amino acids 486 to 594 (109 residues), 40.7 bits, see alignment E=3.6e-14

Best Hits

KEGG orthology group: None (inferred from 54% identity to reh:H16_B0524)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JRF8 at UniProt or InterPro

Protein Sequence (614 amino acids)

>Ac3H11_2999 Two-component hybrid sensor and regulator (Acidovorax sp. GW101-3H11)
MEPVSAPAAPARAPATPAQEPAQASLQTVSMAGQARLLEMTYQRLHTSIMVLPLVALALT
LFYQLQHDARWMWGWFGFYVVFAATSHRLRRVFRQDQGRRDAADLMRRWRPRLELCALIH
GAGTTAPVVIAAGHASYDFALLLLVTNAAILAGNATHQTPVLSVFMRFFMTGWNASLLVQ
PWLFPQHWYFILPLSLLHTFTMYRHSHTAHRFFVHQVWLEERGQQLSAQYREARDAAEAA
LAEKNRFLSTAAHDLRQPVHAMGLLTEAIALRNRDTALAAPLSDLRLNLQSVQLMFNSLL
DLSKIESGQVAVRPEPLLLRPFFNELEIQFLAEARSRGLRLRLHMPPAGAAVQADAALLR
QSLSNLVHNALRYTPQGGVLIGARRRQGHWRIEVWDTGLGVALEDRARIYQPFYRPQHAW
HINREGHGLGLAVVARCVDLMGAQHGLQSRLGTGSCFWLQLPAAAPGPCPASPRSQPARP
LQGRCLILDDDPHVLGAWSALLSSWGLQVCLASDARQAFAHVDAGQAIDVVLCDQRLRSG
ESGFDVLLALLARCPQARGAMVSGEFDAPALRRAEDEGYLVLKKPVDVADLQALLSRWLA
APVDAAAAVEVPQP