Protein Info for Ac3H11_299 in Acidovorax sp. GW101-3H11

Annotation: EAL domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 PF00563: EAL" amino acids 98 to 214 (117 residues), 31.8 bits, see alignment E=9.7e-12 PF08668: HDOD" amino acids 232 to 342 (111 residues), 47.8 bits, see alignment E=1.2e-16

Best Hits

KEGG orthology group: K07181, putative signal transduction protein containing EAL and modified HD-GYP domains (inferred from 84% identity to vei:Veis_1719)

Predicted SEED Role

"EAL domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JN15 at UniProt or InterPro

Protein Sequence (426 amino acids)

>Ac3H11_299 EAL domain protein (Acidovorax sp. GW101-3H11)
MSSTPEQDTPDAASPAVEPVDENLAIIARQAIVDESRAVYGYELFDRSTASDSHTAASDA
ALLFNALSYAGTEALVGKKTVFINCTHDSLSGGHLELIHPEKVVLEVPPLPDGATPEEIE
GRLPTLEALRTRGFRLAFDQQALKRAYTSWLPLAAFIKLDMQAFKPELAAPLVKFATTHS
KATLVAEKVETAEQYELMKGLGVKLFQGYWFALPSLVKATTIRPSQATIIQLINLVRKQA
STAEIEDLLKKDPTLSFNLLRFINSSGFGLSCEITSFRHAVMILGLKKLFRWAALLMTTS
RAGGAPPAVGQTAVVRGRLMELLAAELLPPEECDNAFVVGVFSLLDTMLGVPLEKALESV
ALPEPVMDALLRGTGVFAPFLELTKACESGDEVAFAKNADALHLSNRQVNWAHLQALTWA
ESLNEE