Protein Info for Ac3H11_298 in Acidovorax sp. GW101-3H11
Annotation: EAL domain protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K07181, putative signal transduction protein containing EAL and modified HD-GYP domains (inferred from 82% identity to aaa:Acav_1335)Predicted SEED Role
"EAL domain protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A165JN01 at UniProt or InterPro
Protein Sequence (422 amino acids)
>Ac3H11_298 EAL domain protein (Acidovorax sp. GW101-3H11) MTSPTTPGLSLTPPPPGNQSSVAMIARQAIVNAQQVVVGYELFNRSRSGAAHTAATDVIL VFTALSHAGTEELVGKKLIFVNCTHESLSGGHLELVDPDKVVLEIPPLGHAAAEEVATRM PILAELRNRGFHLAFNHTVLQSAYAPWLPLADYIKLDLSVLAPDQLAVLISYAGRNSQAE LIAEKVETAQQYDMVSSQGVQMFQGYWFARPSLVEAKLLAPSQASIIELINQVRKQASTD DIEETLKKDAGLAFNLMRLINSAGFGLSREITSFRQAVMLMGLKKLFRWAALLLTASRAG GTPSSVGQTAVVRGRLMELLALETLPAEEADQAFVVGIFSLLDVMLSMPMESALGLLNVP EPVAAALLRREGFLGDLLTLAEACESSDDAVFDRTAGLLHLTSQQINFAHLQALAWADHL GD