Protein Info for Ac3H11_2914 in Acidovorax sp. GW101-3H11

Annotation: Arginine decarboxylase (EC 4.1.1.19); Ornithine decarboxylase (EC 4.1.1.17); Lysine decarboxylase (EC 4.1.1.18)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03709: OKR_DC_1_N
  • amino acids 21 to 143 (123 residues), 111.9 bits, E=2.9e-36
• PF01276: OKR_DC_1
  • amino acids 149 to 591 (443 residues), 482.4 bits, E=1.6e-148
• PF03711: OKR_DC_1_C
  • amino acids 618 to 743 (126 residues), 159.1 bits, E=1.1e-50

Best Hits

KEGG orthology group: K01581, ornithine decarboxylase [EC: 4.1.1.17] (inferred from 94% identity to ajs:Ajs_2762)

Predicted SEED Role

"Arginine decarboxylase (EC 4.1.1.19); Ornithine decarboxylase (EC 4.1.1.17); Lysine decarboxylase (EC 4.1.1.18)" (EC 4.1.1.17, EC 4.1.1.18, EC 4.1.1.19)

MetaCyc Pathways

• superpathway of arginine and polyamine biosynthesis (15/17 steps found)
• putrescine biosynthesis III (2/2 steps found)
• arginine dependent acid resistance (1/1 steps found)
• cadaverine biosynthesis (1/1 steps found)
• superpathway of polyamine biosynthesis I (6/8 steps found)
• superpathway of putrescine biosynthesis (3/4 steps found)
• aminopropylcadaverine biosynthesis (2/3 steps found)
• L-lysine degradation X (4/6 steps found)
• L-arginine degradation III (arginine decarboxylase/agmatinase pathway) (1/2 steps found)
• putrescine biosynthesis I (1/2 steps found)
• superpathway of polyamine biosynthesis II (5/8 steps found)
• spermidine biosynthesis III (2/4 steps found)
• L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) (1/3 steps found)
• putrescine biosynthesis II (1/3 steps found)
• L-lysine degradation I (3/7 steps found)
• bisucaberin biosynthesis (1/5 steps found)
• desferrioxamine B biosynthesis (1/5 steps found)
• desferrioxamine E biosynthesis (1/5 steps found)
• lupanine biosynthesis (1/5 steps found)
• superpathway of ornithine degradation (3/8 steps found)
• superpathway of L-arginine and L-ornithine degradation (6/13 steps found)
• superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (4/11 steps found)
• superpathway of hyoscyamine (atropine) and scopolamine biosynthesis (4/16 steps found)
• superpathway of L-lysine degradation (10/43 steps found)

KEGG Metabolic Maps

• Alkaloid biosynthesis II
• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Glutathione metabolism
• Lysine degradation
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.17 or 4.1.1.18 or 4.1.1.19

Sequence Analysis Tools

See A0A165L2M8 at UniProt or InterPro

Protein Sequence (761 amino acids)

>Ac3H11_2914 Arginine decarboxylase (EC 4.1.1.19); Ornithine decarboxylase (EC 4.1.1.17); Lysine decarboxylase (EC 4.1.1.18) (Acidovorax sp. GW101-3H11)
MKFRFPIIIIDEDYRSENTSGLGIRALAQAIETEGFEVVGVTSYGDLSQFAQQQSRASAF
ILSIDDEEFTVGEGLDPIVLSLRNFIGEVRRKNADVPIYVHGETKTSRHLPNDILRELHG
FIHMFEDTPEFVARHIIREAKSYLESVQPPFFKALLDYAEDGSYSWHCPGHSGGVAFLKS
PVGQMYHQFYGENMLRADVCNAVEELGQLLDHNGAIGESERNAARIFNADHCFFVTNGTS
TSNKMVWHHTVAPGDVVVVDRNCHKSILHSIIMTGAIPVFMKPTRNHFGIIGPIPQSEFE
PAAIQAKIKANPLLKGVDAKKVKPRVLTLTQSTYDGVLYNTETIKGMLDGYVDNLHFDEA
WLPHAAFHPFYGSYHAMGKKRTRPKYSVTYATQSIHKLLAGISQASHVLVQDSQTAKLDR
HLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESLLEALDFRRAMRQVEEDF
GKNDWWFKVWGPDKLVDEGLGRAEDWIIRSDGKGKKNGSKWHGFGQLADGFNMLDPIKST
IVTPGLNLDGKFDKTGIPASIVTKYLAEHGVVVEKTGLYSFFIMFTIGITKGRWNTLLTA
LQQFKDDYEKNQPMWRILPEFCQQHKRYERMGLRDLCQHVHEMYAKYDIARLTTEMYLSD
LTPAMKPSDAYAHIAHRTTERVEIDNLEGRITVGLVTPYPPGIPLLIPGEVFNKKIVDYL
KFAREFAKLCPGFETDIHGLVEVEDESGQVRYYADCVAGKP