Protein Info for Ac3H11_2781 in Acidovorax sp. GW101-3H11

Annotation: Tricarboxylate transport protein TctC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF03401: TctC" amino acids 54 to 324 (271 residues), 265.2 bits, see alignment E=2.7e-83

Best Hits

Swiss-Prot: 32% identical to YTCB_PSESQ: UPF0065 protein in tcbD-tcbE intergenic region from Pseudomonas sp. (strain P51)

KEGG orthology group: None (inferred from 50% identity to vap:Vapar_5654)

Predicted SEED Role

"Tricarboxylate transport protein TctC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165L072 at UniProt or InterPro

Protein Sequence (331 amino acids)

>Ac3H11_2781 Tricarboxylate transport protein TctC (Acidovorax sp. GW101-3H11)
MFTYTHRLLARAAITLACGLAAVLSATQALAQDYPNKPLKLIVPAGAGTSTDIVARLMGE
GLARELGQPVVVENKTGASGNIAHELVAKSPADGYTLILTNTGPFSINKALYKKINFDPI
KDFTPLTMIGYTPTLLLVRANAPWHSVAELVQYAKDNPDKVTYASAGNGTTGHLAGELVK
ATSNTKMVHVPYKEGAQAVTSVIGGQTDFMFYHPAVAMPQIQAGKLRALGLSSVAKSPAA
PGVKPLDEQGFPGFDLTGWWAVAGPASLPPAVMQKLVQAGDKVVKSGDFQTRLAAVGIDP
LVMTQPEFARFAASELEKWGGVVRLSGAQVD