Protein Info for Ac3H11_257 in Acidovorax sp. GW101-3H11

Annotation: RND efflux system, outer membrane lipoprotein, NodT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 27 to 484 (458 residues), 356.2 bits, see alignment E=1.4e-110 PF02321: OEP" amino acids 98 to 275 (178 residues), 57.4 bits, see alignment E=8.5e-20 amino acids 302 to 482 (181 residues), 100.7 bits, see alignment E=4.6e-33

Best Hits

KEGG orthology group: None (inferred from 80% identity to aaa:Acav_1399)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein, NodT family" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JM53 at UniProt or InterPro

Protein Sequence (498 amino acids)

>Ac3H11_257 RND efflux system, outer membrane lipoprotein, NodT family (Acidovorax sp. GW101-3H11)
MTDLLLTKNSTDGALAARKRSLLAPLAAALVLAGCMTQPVAPAPHAGVPVPASFTAGGDA
LPTAPWTVAAPAEAQPRGEWWLGFQDPVLADLVLRAGTANTSIQQAAARLAEARTLLRSA
DAARSVQVGASAGVTRQAGAATTGSAAPATLGTAGLNASYELDLFGRLSQTSDAARLDAD
AREALLQSTRLMVQADVAQTYLQLRAVQAEQVLVQESLAAYQDTLRLTQRRLQAGDVAEL
DVARVLTEVAATESDALALQRQQALLTNALAVLAGEVASGFVLPPANSDAALPVIPPGVP
GTVLARRPDVSAAQAAVLAAQARVGVAQKAWFPAVTLTGNAGHASPELGDLFKWSARAWG
VSALLSLPIFDGGQRDAQIEGAKARLEAALADHRGQVLNAFRDVEDQLTSLRLLSGQAEA
QGRAVTAARRATQLSDVRYRNGLVSQLELLDARRSELRNRRQELQVRTAQYVATVGLIRA
LGGGWGDLPAVKVAQVLQ