Protein Info for Ac3H11_2532 in Acidovorax sp. GW101-3H11

Annotation: FIG00581870: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00135: COesterase
  • amino acids 32 to 550 (519 residues), 308.2 bits, E=1.4e-95
• PF20434: BD-FAE
  • amino acids 127 to 246 (120 residues), 27.5 bits, E=2.2e-10

Best Hits

KEGG orthology group: K03927, carboxylesterase type B [EC: 3.1.1.1] (inferred from 68% identity to dac:Daci_3304)

Predicted SEED Role

"FIG00581870: hypothetical protein"

MetaCyc Pathways

• methylsalicylate degradation (2/2 steps found)
• aspartame degradation (1/2 steps found)
• methyl indole-3-acetate interconversion (1/2 steps found)
• superpathway of methylsalicylate metabolism (1/5 steps found)
• retinol biosynthesis (2/7 steps found)

KEGG Metabolic Maps

• Alkaloid biosynthesis II
• Drug metabolism - other enzymes

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.1

Sequence Analysis Tools

See A0A162F6I0 at UniProt or InterPro

Protein Sequence (568 amino acids)

>Ac3H11_2532 FIG00581870: hypothetical protein (Acidovorax sp. GW101-3H11)
MIDVRKRVPWLGAVVCVLALAGCGGGSGSAPEVRETVYGTVRGVDDSAVTGTYAWKGMPF
AKPPVGDLRWQPPAEPAAWAGERSATRFGNACLQMGRLYGPGANNRFDDTIGQTLGTPVG
NEDCLTLNIWRPATNQDNLPVLLFLHGGSAISGYTADPVYDGAALARAANAVVVTANYRL
DVLGFLQLPQLHSGSQAYTGNYALLDNVQALTFIQRNIAKFGGNAANVTLMGQSAGAINV
LALLTAPQAAGLFHKIVPISGGISLASNLPAGSIPTLNPASKYAAQSGALLAALALADGL
APDAAAAATLVAGWTPAQTASYLRGKDGRVVLQTVMQKGLTGSGPIPDGVVVPTNPIAEI
AAGRYHKVPVLSGYTQDEAKLFAPFLALLGGKPGLKISDAERFAMTQGFNPDAPTTLTVA
DIIDPSYLPIAAPSTGYNARMKLLGSVFFEPSRDNLLGTLRTQQANVWSYQFNWAQQPAP
WNDVYGAAHGFDLPFVFGNFGPSLLAKAANSTANQPGRLALSGVMMDSVRAFVHTGNPNH
TGLGEEWQPWPRKFIFDADQKATRLSVQ