Protein Info for Ac3H11_2364 in Acidovorax sp. GW101-3H11

Annotation: Ferrichrome-iron receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 731 signal peptide" amino acids 1 to 44 (44 residues), see Phobius details PF07715: Plug" amino acids 82 to 185 (104 residues), 81.4 bits, see alignment E=1e-26 TIGR01783: TonB-dependent siderophore receptor" amino acids 84 to 731 (648 residues), 362.8 bits, see alignment E=2.1e-112 PF00593: TonB_dep_Rec" amino acids 256 to 700 (445 residues), 216.7 bits, see alignment E=1.7e-67

Best Hits

Swiss-Prot: 42% identical to CNTO_PSEAB: Metal-pseudopaline receptor CntO (cntO) from Pseudomonas aeruginosa (strain UCBPP-PA14)

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 74% identity to vap:Vapar_2068)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165L5E1 at UniProt or InterPro

Protein Sequence (731 amino acids)

>Ac3H11_2364 Ferrichrome-iron receptor (Acidovorax sp. GW101-3H11)
LDWFAMRSSSSPDSSSRPAPLPRPTLTALAAAALLASLHPAWAADGDVVTPPTLSAVDVV
GRSASGTYYADEAEGAKTSLPLRELPQSVRVMSRQTLDDLGATRLDDVLDYVGGVSRQNN
FGGLWDNIAIRGLPGNENTGMATLLNGFSSNRGFNAPRDLAGVERVEFLKGPAAALYGSS
EPGGTLNIVSKKPLWKAAHSVEAYAGSYGLGRAALDTTGPISDRLAYRLNVAVEDKGSFR
DHVRAQRQVVAPALTWKLSPDTVLEYTAEFLRHATPLDRGVVAVNNRLGPVPASRFLGEP
ADGDVTVTNQTHQLVLSHEWNPDWRSRVGLSYRETGMEGFSTEATALQANGRTLTRQRRY
RDFQSDDVAVQAELQGNLRTGGLEHELLVGVESYRFSMDSVMLRVNPSAAAPYAIDIFNP
VYGQAQPTPGRNTDTLEKQRNTALYVQDTLKLGEQWRVMAGLRADNYEQSLQNRITHRTT
AQSPSAVSPRLGVSWLPTQGWTVYANAGSSFRPNTGSNVAGNGFDPEKSRALELGAKWES
TDQRLGATAALFDITKRNVLTSDPLNAGFSAAAGEVRSRGLELDLSGRVSAHWRVNASLV
FNDVEVTRDNTLEVGGRLLNVPKVNGSVLAVYENALANGQRYGVGGGVTHMGKRLGQART
QAEANAGTAAFELPSYTTAKLMAYWRLSPTLNLSLDVDNVFDKVHYTSSYSRVWVAPGAA
RTVTVGLQAKF