Protein Info for Ac3H11_232 in Acidovorax sp. GW101-3H11

Annotation: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 TIGR03140: alkyl hydroperoxide reductase subunit F" amino acids 1 to 517 (517 residues), 774.8 bits, see alignment E=1.9e-237 PF13192: Thioredoxin_3" amino acids 120 to 193 (74 residues), 45 bits, see alignment E=2.8e-15 PF07992: Pyr_redox_2" amino acids 213 to 504 (292 residues), 162 bits, see alignment E=6.5e-51 PF13738: Pyr_redox_3" amino acids 300 to 487 (188 residues), 54.7 bits, see alignment E=3e-18 PF00070: Pyr_redox" amino acids 357 to 431 (75 residues), 51.3 bits, see alignment E=4.2e-17

Best Hits

Swiss-Prot: 70% identical to AHPF_PSEPK: Alkyl hydroperoxide reductase subunit F (ahpF) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K03387, alkyl hydroperoxide reductase subunit F [EC: 1.6.4.-] (inferred from 86% identity to ctt:CtCNB1_1177)

MetaCyc: 62% identical to alkyl hydroperoxide reductase, AhpF component (Escherichia coli K-12 substr. MG1655)
RXN-8506 [EC: 1.5.1.37]; R4-RXN [EC: 1.5.1.37, 1.11.1.26]

Predicted SEED Role

"Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)" in subsystem Thioredoxin-disulfide reductase (EC 1.6.4.-)

Isozymes

Compare fitness of predicted isozymes for: 1.6.4.-

Use Curated BLAST to search for 1.11.1.26 or 1.5.1.37 or 1.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JLD2 at UniProt or InterPro

Protein Sequence (525 amino acids)

>Ac3H11_232 Alkyl hydroperoxide reductase protein F (EC 1.6.4.-) (Acidovorax sp. GW101-3H11)
MLDEQLKTQLSAYLERVQQPFELVASLDDSDTAREMRELLTTIQSLRSDKITLRTDGNDA
RKPSFSLQRVGATNSLRFAGLPLGHEFTSLVLALLWTGGHPPKVEPEVIEQIAALEGDFN
FEVYMSLTCHNCPDVVQALSLMAIVNPQVKTTVIEGGAFQQEVTEREIMAVPMVFLNGKV
FGSGRMSVEEIVAKLDTGAAARDAAKLSAKAPYDVLIVGGGPAGAAAAVYAARKGIRTGV
AAERFGGQVNDTLAIENYISVLETDGPKFAAALEAHTRAYDVDIMNLQRADKLIPAAEPG
GLIEVQLANGGTLQSKTVILSTGARWRNVNVPGEAEYKNKGVAYCPHCDGPLFKGKRVSV
IGGGNSGVEAAIDLAGIVQHVTLIEFADQLKADAVLVNKLKSLANVTIHTNAQTTEITGA
DGKVNGLKYKDRATNVEHLVPLEGVFVQIGLVPNTEWLKGTVELSRFGEIIVDAHGRTNL
PGVFAAGDCTTVPFKQIVIAAGDGSKAALSAFDHLIRMPVVAGAV