Protein Info for Ac3H11_231 in Acidovorax sp. GW101-3H11

Annotation: TonB-dependent hemin , ferrichrome receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 762 signal peptide" amino acids 1 to 48 (48 residues), see Phobius details TIGR01785: TonB-dependent heme/hemoglobin receptor family protein" amino acids 64 to 762 (699 residues), 371.2 bits, see alignment E=1.1e-114 TIGR01786: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein" amino acids 69 to 762 (694 residues), 398.3 bits, see alignment E=6.8e-123 PF07715: Plug" amino acids 79 to 196 (118 residues), 84.1 bits, see alignment E=1.5e-27 PF00593: TonB_dep_Rec" amino acids 300 to 723 (424 residues), 225.5 bits, see alignment E=3.8e-70 PF14905: OMP_b-brl_3" amino acids 390 to 726 (337 residues), 40 bits, see alignment E=4.1e-14

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 61% identity to vpe:Varpa_2070)

Predicted SEED Role

"TonB-dependent hemin , ferrichrome receptor" in subsystem Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JLC7 at UniProt or InterPro

Protein Sequence (762 amino acids)

>Ac3H11_231 TonB-dependent hemin , ferrichrome receptor (Acidovorax sp. GW101-3H11)
VAQAFRTPPFSSRRAQAHASHPSLQGRLRPLAWLVACACAAIGSAHAQGHAQDVAQLVAA
GPVLKEVVISGSRSEQDRDELPMSIDVINAQAIEEGQVRDIRDVARELPNLSVTRSPARF
SLASGSTGREQNAGFNIRGLDGNRVLMMVDGIRLPRSYVFSANAFGRDYLDIGLLQRIEV
VRGATSALYGSDGMAGLVNFITAEPSAFLEGDKRIGGRVSLGYDGDEHGERVGATVAGKA
GDTVQWLLGGNVTRASELDNMGTNSAANADRTRPNPQKDRSGALLGKVVLTPGGGQRHVF
TLEHVDKTSDYELLTARSKPPLAATSVLGSTSFTDMQRSRATWEGSWRVNSALADDVKAT
LSWQDAHSREYITEDRNTAADRVRDVTYDERTWQANLQGSKVLRNGSRWVQKITYGLDYA
SAQVENLQTGVTPPTGETFPLKRFPDTTETSTALYVQDEFVSGPWSITPGVRFDTFRIKA
DQAGFGAQAVSLSGNATSPKFGVLYRATDQWSVFGNYAAGFRAPNAGQVNAFFENPVGNY
RTVPNANLKPEKSQNFELGVRGRMERLSIEAAAFTGRYKDFIEDLRQVSGTGAPGNPLVF
QSVNIGRVKLSGFEVKGDMRWGQWAGGQWSSPFAYGQTRGRDTATGKPVNTVVPSRLTAG
LRYDTGGWMARLDMTHAAAKKARDVSVATGSTQFLTPSYTVLDLAAQWRIRKDLRLNAGI
YNLTDKKHWRWADVRGLAANASFIDAYSQPGRAVRVSLVADF