Protein Info for Ac3H11_2146 in Acidovorax sp. GW101-3H11

Annotation: Protoporphyrinogen IX oxidase, novel form, HemJ (EC 1.3.-.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 145 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 50 to 70 (21 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 120 to 142 (23 residues), see Phobius details PF03653: UPF0093" amino acids 2 to 145 (144 residues), 142.5 bits, see alignment E=6.4e-46

Best Hits

KEGG orthology group: K08973, putative membrane protein (inferred from 85% identity to dia:Dtpsy_0263)

Predicted SEED Role

"Protoporphyrinogen IX oxidase, novel form, HemJ (EC 1.3.-.-)" (EC 1.3.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.-.-

Use Curated BLAST to search for 1.3.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168F5B2 at UniProt or InterPro

Protein Sequence (145 amino acids)

>Ac3H11_2146 Protoporphyrinogen IX oxidase, novel form, HemJ (EC 1.3.-.-) (Acidovorax sp. GW101-3H11)
MLWVKAFHIVFVASWFAGLFYLPRIFVNLAMVAPGSVAERDRLLLMARKLLRFTTLLAVP
ALALGVWLWMGYGIGRGPASQGNGWMHAKLAVVVLVIGYHHACAVLLRKLADGTCRKSHV
WFRWFNEAPVLLLLLAVVLVVVKPF