Protein Info for Ac3H11_2095 in Acidovorax sp. GW101-3H11

Annotation: ATP synthase alpha chain (EC 3.6.3.14)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 TIGR00962: ATP synthase F1, alpha subunit" amino acids 3 to 517 (515 residues), 806.6 bits, see alignment E=4.5e-247 PF02874: ATP-synt_ab_N" amino acids 26 to 97 (72 residues), 53 bits, see alignment E=6e-18 PF00006: ATP-synt_ab" amino acids 154 to 380 (227 residues), 266.3 bits, see alignment E=3.1e-83 PF00306: ATP-synt_ab_C" amino acids 387 to 512 (126 residues), 148.6 bits, see alignment E=1.8e-47

Best Hits

Swiss-Prot: 94% identical to ATPA_ACIAC: ATP synthase subunit alpha (atpA) from Acidovorax citrulli (strain AAC00-1)

KEGG orthology group: K02111, F-type H+-transporting ATPase subunit alpha [EC: 3.6.3.14] (inferred from 94% identity to aav:Aave_0370)

MetaCyc: 69% identical to ATP synthase F1 complex subunit alpha (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"ATP synthase alpha chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A162DJU9 at UniProt or InterPro

Protein Sequence (517 amino acids)

>Ac3H11_2095 ATP synthase alpha chain (EC 3.6.3.14) (Acidovorax sp. GW101-3H11)
MQLNPAEISELIKSRIEGLAASSDIRNQGTVVSVSDGIVRVHGLSDVMAGEMLEFPATKD
GQPSYGLALNLERDSVGAVILGEYEHISEGDTVKCTGRILEVPVGPELVGRVVNALGQPI
DGKGPINAKLTDVIEKVAPGVIARKSVDQPLQTGLKSIDSMVPVGRGQRELIIGDRQTGK
TAVAIDAIIAQKGQGVTCIYVAIGQKASSIKNVVRALEQAGAMEYTIVVAASASESAAMQ
YVSAYSGCTMGEYFRDRGQDALIVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHS
RLLERAARVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFL
ETSLFNAGIRPAINAGISVSRVGGAAQTKLVKNLSGGIRTDLAQYRELAAFAQFASDLDE
ATRKQLDRGARVTELLKQAQYSPLSISLMGATLFAVNKGFMDDIDVKKVLDFEHGLHQFL
KTSHAALLAKLEQAKAMDKDAEAELTAAVAAFKKSFA