Protein Info for Ac3H11_2048 in Acidovorax sp. GW101-3H11

Annotation: Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 TIGR01891: amidohydrolase" amino acids 23 to 388 (366 residues), 329.2 bits, see alignment E=1.7e-102 PF01546: Peptidase_M20" amino acids 85 to 398 (314 residues), 142.1 bits, see alignment E=2.3e-45 PF07687: M20_dimer" amino acids 197 to 294 (98 residues), 25.4 bits, see alignment E=1.1e-09

Best Hits

Swiss-Prot: 40% identical to ILL3_ORYSJ: IAA-amino acid hydrolase ILR1-like 3 (ILL3) from Oryza sativa subsp. japonica

KEGG orthology group: K01451, hippurate hydrolase [EC: 3.5.1.32] (inferred from 86% identity to vei:Veis_1301)

MetaCyc: 43% identical to beta-tabtoxin peptidase (Pseudomonas syringae)
3.4.11.-

Predicted SEED Role

"Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit A" in subsystem p-Aminobenzoyl-Glutamate Utilization

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.32

Use Curated BLAST to search for 3.5.1.32

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KPI9 at UniProt or InterPro

Protein Sequence (405 amino acids)

>Ac3H11_2048 Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit A (Acidovorax sp. GW101-3H11)
MQSLKYKAGGRAFSHIAQFHPELTALRRDLHAHPELGFEEVYTSKRVKEALTLCGVDEIH
DGIGRTGVVGVIRGRSTSSGSMVGLRADMDALPLAEHNDFSWKSCKPGLMHGCGHDGHTA
MLVGAARYLAETRNFDGTAVLVFQPGEEGFAGARVMMEDGLFDRFPVQSIYAMHNWPAMK
PGTVGINAGPMMAAADRFTIEITGRGGHGAHAYQTVDVLVVAAHIITAAQSIVSRNVRPI
ESAVVSICAAQAGDLGAFSVLPGSATLVGTVRTFDPVVQEMVEKRLKELCNAIALGFGAT
ATVHYERIYPATINSESEAIFAGDVAESLLGADHVVRDLEPSMGAEDFAFMLQTRPGAYL
RLGQGTGASGSALHNSRYDFNDDILPLGAALHASLIEQSMPLAMP