Protein Info for Ac3H11_1980 in Acidovorax sp. GW101-3H11

Annotation: Homolog of eukaryotic DNA ligase III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 320 PF09414: RNA_ligase" amino acids 51 to 242 (192 residues), 116.4 bits, see alignment E=8.2e-38

Best Hits

KEGG orthology group: None (inferred from 60% identity to pct:PC1_2133)

Predicted SEED Role

"Homolog of eukaryotic DNA ligase III"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (320 amino acids)

>Ac3H11_1980 Homolog of eukaryotic DNA ligase III (Acidovorax sp. GW101-3H11)
MAKTLSNTPVAAQLSLPILRYPRTPHLEGSRQQAGDAPDVQPLAPLAGHHAVIEEKMDGA
NCAISFTEGGELCLQSRGHYLLGGARERQFAALHPWARAHEAGLLACLQDRYVLYGEWMF
AKHAMFYDRLPHYLLEFDVWDRMEQCFLSTSRRHALLAGLPVVSVPVLYEGPMPQRADWL
WSLVGHSLARTPRWSEALDTTIERLALPHALCRQQSDPSPLAEGLYVKLEDEHQVLARFK
LVRADFVQHILDSGSHHSERPIVPNGLAPGVDLYAPQLRCNWADLGAQCLYGLEALQAHH
ANDAARVVRRARKGGAPWRR