Protein Info for Ac3H11_1969 in Acidovorax sp. GW101-3H11

Annotation: N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details TIGR01891: amidohydrolase" amino acids 49 to 432 (384 residues), 359 bits, see alignment E=1.5e-111 PF01546: Peptidase_M20" amino acids 107 to 440 (334 residues), 129.9 bits, see alignment E=1.3e-41 PF07687: M20_dimer" amino acids 236 to 335 (100 residues), 38.8 bits, see alignment E=7.6e-14

Best Hits

KEGG orthology group: None (inferred from 82% identity to del:DelCs14_5100)

Predicted SEED Role

"N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)" in subsystem Lysine Biosynthesis DAP Pathway (EC 3.5.1.47)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165KMV0 at UniProt or InterPro

Protein Sequence (447 amino acids)

>Ac3H11_1969 N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47) (Acidovorax sp. GW101-3H11)
MHKPLSAIAIAAGLVASGLTFVSSAQAQALDATGLQAIDAAVNAVAPKMVNWRRDIHAYP
ELSGQEVRTAKLVAEHLKKLGMEVQTGVGGTGVVGTLKGGLPGKVVALRADMDALPVLEN
TGLPFASKAKATYLGKEVPVMHACGHDAHTAMLMGAAEVLAGMKAQLPGTVKFIFQPAEE
GAPVEADANGKVPSFGAKAMIEAGALKDVQAIYGLHITSNLPGGVVGYRSGPLMAGSDNI
TIHVEGRGGHGSSPWATIDPIVAASQVVMGLQTVVSRQLNISQEPAVVTIGQIQGGTRYN
IIPDKVEMMGTLRTFDEDMRQEALKRITTTAESIAAASGAKASVRFGPVAYPVTTNPAQL
TQASLPALNLAMGGKTMVIPKVAGSEDFSEFQKVVPGFFYFLGAPPKGKEFAKAPPNHSA
LFDIDEDQLPTGARSLAALAVDFLQRK