Protein Info for Ac3H11_18 in Acidovorax sp. GW101-3H11

Annotation: trypsin-like serine protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 473 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF13365: Trypsin_2" amino acids 101 to 239 (139 residues), 93.7 bits, see alignment E=9.8e-31

Best Hits

Predicted SEED Role

"trypsin-like serine protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165HYE1 at UniProt or InterPro

Protein Sequence (473 amino acids)

>Ac3H11_18 trypsin-like serine protease (Acidovorax sp. GW101-3H11)
MPFPLIRPLRLATSSLVLLLCALAAHAQNAPSTATASTPAPRPAGSSPVDGTAQTPAAAA
PTAADAALLSRDARRIYELSRDKLVQIRTLLRNAGTQASIGSGFFVSADGLIVTNFHVAS
QLALEPERYRGVYVTMEGQEGEVELLAFDVQRDLAVLRAKGRTAAAPVLGFRPADEALAQ
GERIYSLGNPLDIGFAVTEGTYNGLVKRSFYPRIFFGGTLNPGMSGGPAVDDAGRVLGVN
VAKRLDGEQVSFLIPAEFAQALVQRAANAQPITQAAHAEMTRQLVEHQQVLTDRFLKAPF
REQRHGSYRVPVPDDALARCWGSGRDPSFPGLNLERTQCRADSDVVAGDFNTGAVRLSYE
AYNAPTLGAARFARMYSQSFANEQLPTRGNRHQTAAECTERFVDPGSLPLRAVVCLSAYR
KLTGLYNMTVLVTSVNQPTQGVLGRLDVQGVAFDNGMKLASHYLKAFRWEAAP