Protein Info for Ac3H11_1510 in Acidovorax sp. GW101-3H11

Annotation: Thiol peroxidase, Bcp-type (EC 1.11.1.15)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00578: AhpC-TSA
  • amino acids 5 to 132 (128 residues), 116.9 bits, E=5.6e-38
• PF08534: Redoxin
  • amino acids 5 to 105 (101 residues), 41.1 bits, E=1.7e-14

Best Hits

Swiss-Prot: 49% identical to BCP_XANCP: Peroxiredoxin Bcp (bcp) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K03564, peroxiredoxin Q/BCP [EC: 1.11.1.15] (inferred from 96% identity to aaa:Acav_1253)

MetaCyc: 38% identical to thiol peroxidase (Escherichia coli K-12 substr. MG1655)
1.11.1.15-RXN [EC: 1.11.1.24]

Predicted SEED Role

"Thiol peroxidase, Bcp-type (EC 1.11.1.15)" in subsystem Thioredoxin-disulfide reductase (EC 1.11.1.15)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.15

Use Curated BLAST to search for 1.11.1.15 or 1.11.1.24

Sequence Analysis Tools

See A0A165K811 at UniProt or InterPro

Protein Sequence (161 amino acids)

>Ac3H11_1510 Thiol peroxidase, Bcp-type (EC 1.11.1.15) (Acidovorax sp. GW101-3H11)
MAIVVNKPLPEFEANATGGIKVSNTSHLGQILVLYFYPKDNTPGCTTEAMQFRDKYKDFV
KAGAAVFGVSRDNMKSHDDFKEKLELPFELIADTEEKMCHMFGVVKNKIMYGKKVKGIER
STFLIGPDGLLVQEWRGLKVPGHVDEVLKTVKSIKALKKAA