Protein Info for Ac3H11_1489 in Acidovorax sp. GW101-3H11

Annotation: Homoprotocatechuate degradative operon repressor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 154 TIGR02337: homoprotocatechuate degradation operon regulator, HpaR" amino acids 12 to 141 (130 residues), 135.8 bits, see alignment E=3.8e-44 PF12802: MarR_2" amino acids 36 to 94 (59 residues), 44.3 bits, see alignment E=2.5e-15 PF13463: HTH_27" amino acids 37 to 103 (67 residues), 26 bits, see alignment E=1.4e-09 PF01047: MarR" amino acids 37 to 95 (59 residues), 39.4 bits, see alignment E=6.9e-14

Best Hits

Swiss-Prot: 37% identical to FARR_NEIGO: HTH-type transcriptional regulator FarR (farR) from Neisseria gonorrhoeae

KEGG orthology group: None (inferred from 52% identity to bph:Bphy_4194)

Predicted SEED Role

"Homoprotocatechuate degradative operon repressor" in subsystem 4-Hydroxyphenylacetic acid catabolic pathway or Aromatic amino acid degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165K7H2 at UniProt or InterPro

Protein Sequence (154 amino acids)

>Ac3H11_1489 Homoprotocatechuate degradative operon repressor (Acidovorax sp. GW101-3H11)
MDSKPLDLVHRNLPLLFLQARESVFARFRPILNMAGLTEQQWRVVRALLDHGPLEPRQIG
DICRLSSPSLAGILARMDDLGLVLRERLENDQRRVRVSVTPKGKALAASLAPTIEATYRE
LENQLGVEFIAHLYATLDEVIAKLGTAPDSDDGS