Protein Info for Ac3H11_1446 in Acidovorax sp. GW101-3H11

Annotation: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13510: Fer2_4
  • amino acids 1 to 76 (76 residues), 68.3 bits, E=9.7e-23
• TIGR01973: NADH dehydrogenase (quinone), G subunit
  • amino acids 4 to 623 (620 residues), 672.5 bits, E=3.4e-206
• PF00111: Fer2
  • amino acids 7 to 65 (59 residues), 28.5 bits, 2.3e-10
• PF10588: NADH-G_4Fe-4S_3
  • amino acids 84 to 121 (38 residues), 59.5 bits, 3.7e-20
• PF00384: Molybdopterin
  • amino acids 273 to 625 (353 residues), 175.2 bits, E=4e-55

Best Hits

KEGG orthology group: K00336, NADH dehydrogenase I subunit G [EC: 1.6.5.3] (inferred from 82% identity to vei:Veis_2807)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

• NADH to cytochrome bo oxidase electron transfer I (2/2 steps found)
• aerobic respiration I (cytochrome c) (3/4 steps found)
• aerobic respiration III (alternative oxidase pathway) (2/3 steps found)
• NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
• NAD(P)/NADPH interconversion (3/6 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

See A0A165K6P3 at UniProt or InterPro

Protein Sequence (710 amino acids)

>Ac3H11_1446 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) (Acidovorax sp. GW101-3H11)
MVEIELDGQKVEVAEGCMVMHAAEKAGTYIPHFCYHKKLSIAANCRMCLVDVEKAPKPMP
ACATPVTQGMIVRTKSDKAIKAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGSS
SRYEEEKRVVPVKDVGPLISMQEMSRCIHCTRCVRFGQEVAGVMELGMIHRGEHSEITTV
VGDTIDSELSGNMIDICPVGALTSKPFRYSARTWELSRRRSVSPHDSTGSNLIVQVKNHK
VMRVVPLENEAVNECWIADRDRFSYEALNGEDRLTQPMLKQGGVWKEVDWQTALEYVANG
LKNIKNDHGASSIGALVSPHSTVEELYLASALVRGIGSDNIDYRLRNAEFAAPEGIRWLG
TSIASLSTLQRVLVVGSNLRKDHPLFAQRIRQAARHGCQVSAIASVAQDWAMPLQSFVAQ
GAAEWMQTLGGIASAVAQEKGIAAPQGAAAASETAQAIARSLLGGERKAVLLGNAAAHHA
QASQLLALANWIGENTGASVGYLTEAANTVGAQFAGAHPVNGGLNAAQMLSGGLKAAVLL
NTEPVHDSAAGAQAATALAGAEMVVTLSPFKANMEFSDVLLPIAPFTETSGSFVNAEGRL
QSFHAVVRPLGDTRPAWKVLRVLANLLGVPGFDFETSQDVLARATNAPAGTVTQVPAAQL
SNVVKAAPATTAAAGEPVVASIYQLDGLVRRSTSLQLTADARMAREGVAA